mutLBSgeneDB |
Gene summary for NTNG2 |
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Basic gene Info. | Gene symbol | NTNG2 |
Gene name | netrin G2 | |
Synonyms | LHLL9381|Lmnt2|NTNG1|bA479K20.1 | |
Cytomap | UCSC genome browser: 9q34 | |
Type of gene | protein-coding | |
RefGenes | NM_032536.2, | |
Description | bA479K20.1 (novel protein)laminet 2laminet-2netrin G1netrin-G2 | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
HPRD : 17650 | ||
Protein | UniProt: Q96CW9 go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_NTNG2 | |
BioGPS: 84628 | ||
Pathway | NCI Pathway Interaction Database: NTNG2 | |
KEGG: NTNG2 | ||
REACTOME: NTNG2 | ||
Pathway Commons: NTNG2 | ||
Context | iHOP: NTNG2 | |
ligand binding site mutation search in PubMed: NTNG2 | ||
UCL Cancer Institute: NTNG2 | ||
Assigned class in mutLBSgeneDB | C: This gene just belongs to mutLBSgenes. |
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GO ID | GO Term | PubMed ID |
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Ligand binding site mutations for NTNG2 |
![]() We represented ligand binding site mutations only. (You can see big image via clicking.) ![]() |
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LBS | AAchange of nsSNV | Cancer type | # samples | T105 | T105P | OV | 1 |
cf) Cancer type abbreviation. BLCA: Bladder urothelial carcinoma, BRCA: Breast invasive carcinoma, CESC: Cervical squamous cell carcinoma and endocervical adenocarcinoma, COAD: Colon adenocarcinoma, GBM: Glioblastoma multiforme, LGG: Brain lower grade glioma, HNSC: Head and neck squamous cell carcinoma, KICH: Kidney chromophobe, KIRC: Kidney renal clear cell carcinoma, KIRP: Kidney renal papillary cell carcinoma, LAML: Acute myeloid leukemia, LUAD: Lung adenocarcinoma, LUSC: Lung squamous cell carcinoma, OV: Ovarian serous cystadenocarcinoma, PAAD: Pancreatic adenocarcinoma, PRAD: Prostate adenocarcinoma, SKCM: Skin cutaneous melanoma, STAD: Stomach adenocarcinoma, THCA: Thyroid carcinoma, UCEC: Uterine corpus endometrial carcinoma. |
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Protein structure related information for NTNG2 |
![]() Mupro score denotes assessment of the effect of mutations on thermodynamic stability. (ΔΔE<0: mutation decreases stability, ΔΔE>0: mutation increases stability) |
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![]() Blue: mutations of positive stability change. and red : the most recurrent mutation for this gene. |
LBS | AAchange of nsSNV | Relative stability change | T105 | T105P | -1.1977373 |
(MuPro1.1: Jianlin Cheng et al., Prediction of Protein Stability Changes for Single-Site Mutations Using Support Vector Machines, PROTEINS: Structure, Function, and Bioinformatics. 2006, 62:1125-1132) |
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Differential gene expression and gene-gene network for NTNG2 |
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Phenotype information for NTNG2 |
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Disease ID | Disease name | # PubMed | Association type |
umls:C0036341 | Schizophrenia | 5 | Biomarker, GeneticVariation |
umls:C0005586 | Bipolar Disorder | 2 | Biomarker |
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Allele ID | AA change | Clinical significance | Origin | Phenotype IDs |
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Pharmacological information for NTNG2 |
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Drug status | DrugBank ID | Name | Type | Drug structure |
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Ligand ID | Ligand short name | Ligand long name | PDB ID | PDB name | mutLBS | CA | CALCIUM(2+) | 3zyg | A | T105 | CA | CALCIUM(2+) | 3zyg | B | T105 | CA | CALCIUM(2+) | 3zyi | B | T105 |
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Conservation information for LBS of NTNG2 |
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LBS | AA sequence | # species | Species |
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