mutLBSgeneDB

mutLBSgeneDB
mutated Ligand Binding Site gene DataBase

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Gene Summary

Ligand Binding Site Mutation Information

Protein Structure Related Information

Gene Expression and Gene-Gene Network

Phenotype Information

Pharmacological Information

Conservation Information for LBS

Gene summary for NMT2
Gene summary
Basic gene Info.Gene symbolNMT2
Gene nameN-myristoyltransferase 2
Synonyms-
CytomapUCSC genome browser: 10p13
Type of geneprotein-coding
RefGenesNM_004808.2,
DescriptionNMT 2glycylpeptide N-tetradecanoyltransferase 2glycylpeptide N-tetradecanoyltransferase 2 variant 3myristoyl-CoA:protein N-myristoyltransferase 2peptide N-myristoyltransferase 2type II N-myristoyltransferase
Modification date20141207
dbXrefs MIM : 603801
HGNC : HGNC
Ensembl : ENSG00000152465
HPRD : 11948
Vega : OTTHUMG00000017723
ProteinUniProt: O60551
go to UniProt's Cross Reference DB Table
ExpressionCleanEX: HS_NMT2
BioGPS: 9397
PathwayNCI Pathway Interaction Database: NMT2
KEGG: NMT2
REACTOME: NMT2
Pathway Commons: NMT2
ContextiHOP: NMT2
ligand binding site mutation search in PubMed: NMT2
UCL Cancer Institute: NMT2
Assigned class in mutLBSgeneDBC: This gene just belongs to mutLBSgenes.

Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez
GO IDGO TermPubMed ID
GO:0018008N-terminal peptidyl-glycine N-myristoylation25255805


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Ligand binding site mutations for NMT2
Lollipop-style diagram of mutations at LBS in amino-acid sequence.
We represented ligand binding site mutations only. (You can see big image via clicking.)
 
: non-synonymous mutation on LBS, Circle size denotes number of samples.

Cancer type specific mutLBS sorted by frequency
LBSAAchange of nsSNVCancer type# samples
V252V252ASTAD1
V183D185GSTAD1
Y119,H117R118IUCEC1
S258S258LUCEC1
R260R260WUCEC1
cf) Cancer type abbreviation. BLCA: Bladder urothelial carcinoma, BRCA: Breast invasive carcinoma, CESC: Cervical squamous cell carcinoma and endocervical adenocarcinoma, COAD: Colon adenocarcinoma, GBM: Glioblastoma multiforme, LGG: Brain lower grade glioma, HNSC: Head and neck squamous cell carcinoma, KICH: Kidney chromophobe, KIRC: Kidney renal clear cell carcinoma, KIRP: Kidney renal papillary cell carcinoma, LAML: Acute myeloid leukemia, LUAD: Lung adenocarcinoma, LUSC: Lung squamous cell carcinoma, OV: Ovarian serous cystadenocarcinoma, PAAD: Pancreatic adenocarcinoma, PRAD: Prostate adenocarcinoma, SKCM: Skin cutaneous melanoma, STAD: Stomach adenocarcinoma, THCA: Thyroid carcinoma, UCEC: Uterine corpus endometrial carcinoma.


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Protein structure related information for NMT2
Relative protein structure stability change (ΔΔE) using Mupro 1.1
Mupro score denotes assessment of the effect of mutations on thermodynamic stability.
  (ΔΔE<0: mutation decreases stability, ΔΔE>0: mutation increases stability)
: nsSNV at non-LBS: nsSNV at LBS

nsSNVs sorted by the relative stability change of protein structure by each mutation
Blue: mutations of positive stability change. and red : the most recurrent mutation for this gene.
LBSAAchange of nsSNVRelative stability change
V252V252A-1.7483923
V183D185G-1.2116867
R260R260W-0.89325716
H117R118I-0.73171124
Y119R118I-0.73171124
S258S258L-0.32791385
(MuPro1.1: Jianlin Cheng et al., Prediction of Protein Stability Changes for Single-Site Mutations Using Support Vector Machines, PROTEINS: Structure, Function, and Bioinformatics. 2006, 62:1125-1132)

Structure image for NMT2 from PDB

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Differential gene expression and gene-gene network for NMT2
Differential gene expression between mutated and non-mutated LBS samples in all 16 major cancer types

Differential co-expressed gene network based on protein-protein interaction data (CePIN)
* Left PPI network was created from samples with mutations in the LBS of NMT2 and the right PPI network was created from samples without mutations in the LBS of NMT2. Only genes with p-value < 0.05 are shown.
Red circle: input gene. Orange circle: LBSgene. Blue circle: other gene.


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Phenotype information for NMT2
Gene level disease information (DisGeNet)
Disease IDDisease name# PubMedAssociation type
umls:C0029927Ovarian Cysts1Biomarker

Mutation level pathogenic information (ClinVar annotation)
Allele IDAA changeClinical significanceOriginPhenotype IDs

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Pharmacological information for NMT2
Gene expression profile of anticancer drug treated cell-lines (CCLE)
Heatmap showing the correlation between gene expression and drug response across all the cell-lines. We chose the top 20 among 138 drugs.We used Pearson's correlation coefficient.

Gene-centered drug-gene interaction network
Drug information targeting mutLBSgene (Approved drugs only)
Drug statusDrugBank IDNameTypeDrug structure
ExperimentalDB02180Myristoyl-CoaSmall molecule
ExperimentalDB02271S-(2-Oxo)PentadecylcoaSmall molecule
ExperimentalDB070611-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OLSmall molecule
ExperimentalDB07838(Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONESmall molecule

Gene-centered ligand-gene interaction network

Ligands binding to mutated ligand binding site of NMT2 go to BioLip
Ligand IDLigand short nameLigand long namePDB IDPDB namemutLBS


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Conservation information for LBS of NMT2
Multiple alignments for O60551 in multiple species
LBSAA sequence# speciesSpecies
A262RSKRVAPVLIR4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
A262RSKRLAPILIK2Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
A262RSKRLTPLLIK1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A262RSKRLTPVLIK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A281EGIFQAVYTAG4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
A281ENVWQAVYTAG1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A281CDIWHALYTAG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A281YDIWQALHTGG1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
A281CDIWHALYSAG1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
A285QAVYTAGVVLP4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
A285QAVYTAGVLLP1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A285HALYTAGIVLP1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A285QALHTGGVVLP1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
A285HALYSAGIVLP1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
C251EINFLCVHKKL5Homo sapiens, Danio rerio, Bos taurus, Mus musculus, Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
C251EVNFLCIHKKL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
C251EINFLCVHKQL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
C251EINFLCIHKKL1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
F121KHRYQFWDTQP2Homo sapiens, Bos taurus
F121KHKYQFWDTQP1Danio rerio
F121KRRYQFWDTQP1Mus musculus
F121YEDFKFWKTQP1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F121MKDHKFWRTQP1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F121MNEYKFWKTQP1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
F121FEEYKFWKTQP1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
F249MVEINFLCVHK4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
F249SVEINFLCVHK2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
F249CAEVNFLCIHK1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F249SVEINFLCIHK1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
F279NLEGIFQAVYT4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
F279HLENVWQAVYT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F279NKCDIWHALYT1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F279NKYDIWQALHT1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
F279NKCDIWHALYS1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
H117DEAAKHRYQFW2Homo sapiens, Bos taurus
H117DEATKHKYQFW1Danio rerio
H117DEATKRRYQFW1Mus musculus
H117PPKTYEDFKFW1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
H117QKKAMKDHKFW1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
H117QRKDMNEYKFW1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
H117QRKAFEEYKFW1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
I247-KMVEINFLCV2Homo sapiens, Bos taurus
I247-RMVEINFLCV2Danio rerio, Mus musculus
I247KKCAEVNFLCI1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I247-PSVEINFLCV1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
I247-RSVEINFLCV1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
I247-KSVEINFLCI1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
I266VAPVLIREITR4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
I266LTPLLIKEVTR1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I266LTPVLIKEITR1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
I266LAPILIKEVTR1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
I266LAPILIKEITR1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
I269VLIREITRRVN4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
I269LLIKEVTRRCH1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I269VLIKEITRRVN1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
I269ILIKEVTRRVN1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
I269ILIKEITRRVN1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
K259KKLRSKRVAPV4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
K259KKLRSKRLAPI2Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
K259KKLRSKRLTPL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K259KQLRSKRLTPV1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L250VEINFLCVHKK5Homo sapiens, Danio rerio, Bos taurus, Mus musculus, Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
L250AEVNFLCIHKK1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L250VEINFLCVHKQ1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L250VEINFLCIHKK1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
L256CVHKKLRSKRV4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
L256CIHKKLRSKRL2Schizosaccharomyces pombe (strain 972 / ATCC 24843), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
L256CVHKQLRSKRL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L256CVHKKLRSKRL1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
L289TAGVVLPKPVA2Bos taurus, Mus musculus
L289TAGVVLPKPIA1Homo sapiens
L289TAGVVLPKPVS1Danio rerio
L289TAGVLLPSPVS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L289TAGIVLPAPVS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L289TGGVVLPSPVS1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
L289SAGIVLPSPIS1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
N181TLLNENYVEDD4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
N181ELLTENYVEDA1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N181VLLNENYVEDR1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N181VLLNENYVEDK1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
N181VLLNENYIEDK1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
N248KMVEINFLCVH2Homo sapiens, Bos taurus
N248RMVEINFLCVH2Danio rerio, Mus musculus
N248KCAEVNFLCIH1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N248PSVEINFLCVH1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N248RSVEINFLCVH1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
N248KSVEINFLCIH1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
P263SKRVAPVLIRE4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
P263SKRLAPILIKE2Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
P263SKRLTPLLIKE1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P263SKRLTPVLIKE1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q120AKHRYQFWDTQ2Homo sapiens, Bos taurus
Q120TKHKYQFWDTQ1Danio rerio
Q120TKRRYQFWDTQ1Mus musculus
Q120TYEDFKFWKTQ1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q120AMKDHKFWRTQ1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q120DMNEYKFWKTQ1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Q120AFEEYKFWKTQ1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Q280LEGIFQAVYTA4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
Q280LENVWQAVYTA1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q280KCDIWHALYTA1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q280KYDIWQALHTG1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Q280KCDIWHALYSA1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
R257VHKKLRSKRVA4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
R257IHKKLRSKRLT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R257VHKQLRSKRLT1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R257VHKKLRSKRLA1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
R257IHKKLRSKRLA1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
R260KLRSKRVAPVL4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
R260KLRSKRLAPIL2Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
R260KLRSKRLTPLL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R260QLRSKRLTPVL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
S258HKKLRSKRVAP4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
S258HKKLRSKRLAP2Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
S258HKKLRSKRLTP1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
S258HKQLRSKRLTP1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
T270LIREITRRVNL4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
T270LIKEITRRVNK2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
T270LIKEVTRRCHL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
T270LIKEVTRRVNK1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
T284FQAVYTAGVVL4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
T284WQAVYTAGVLL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
T284WHALYTAGIVL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
T284WQALHTGGVVL1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
T284WHALYSAGIVL1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
V183LNENYVEDDDN4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
V183LTENYVEDATA1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V183LNENYVEDRDA1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V183LNENYVEDKDS1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
V183LNENYIEDKDS1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
V252INFLCVHKKLR5Homo sapiens, Danio rerio, Bos taurus, Mus musculus, Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
V252VNFLCIHKKLR1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V252INFLCVHKQLR1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V252INFLCIHKKLR1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
V261LRSKRVAPVLI4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
V261LRSKRLAPILI2Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
V261LRSKRLTPLLI1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V261LRSKRLTPVLI1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V273EITRRVNLEGI4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
V273EITRRVNKCDI2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
V273EVTRRCHLENV1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V273EVTRRVNKYDI1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
W122HRYQFWDTQPV2Homo sapiens, Bos taurus
W122HKYQFWDTQPV1Danio rerio
W122RRYQFWDTQPV1Mus musculus
W122EDFKFWKTQPV1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
W122KDHKFWRTQPV1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
W122NEYKFWKTQPV1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
W122EEYKFWKTQPV1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Y119AAKHRYQFWDT2Homo sapiens, Bos taurus
Y119ATKHKYQFWDT1Danio rerio
Y119ATKRRYQFWDT1Mus musculus
Y119KTYEDFKFWKT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y119KAMKDHKFWRT1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y119KDMNEYKFWKT1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Y119KAFEEYKFWKT1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Y182LLNENYVEDDD4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
Y182LLTENYVEDAT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y182LLNENYVEDRD1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y182LLNENYVEDKD1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Y182LLNENYIEDKD1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Y283IFQAVYTAGVV4Homo sapiens, Danio rerio, Bos taurus, Mus musculus
Y283VWQAVYTAGVL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y283IWHALYTAGIV1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y283IWQALHTGGVV1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Y283IWHALYSAGIV1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Y481LQYYLYNWRCP3Homo sapiens, Bos taurus, Mus musculus
Y481LQYYLYNWKCP1Danio rerio
Y481LNYYIYNYNCP1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y481LNFYLFNYRAK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y481LNFYLFNYRCF1Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Y481LNFYLFNYRAN1Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)


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