Gene: FIGN

Basic information

Tag Content
Uniprot ID A0A286ZU82
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000035046
Ensembl nucleotide ID ENSSSCG00000034262
Gene name Fidgetin, microtubule severing factor
Gene symbol FIGN
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MISSTSVYGL KMQWTPEHAQ WPEQHFDITS TTRSPAHKVE AYRGHLQRTY QYAWANDDIS 60
ALTASNLLKK YAEKYSGILE GPVDRSVLSN YSDAPSGLVN GRKNESEPWQ PSLNSDAVYP 120
MNCVPDVITA SKAGVSSALP PADVSASIGS SPGVASNLTE PSYSSSTCGS HTVPSLHTGL 180
PSQEYAPGYN GSYLHSTYSS QPAPALPSPH PSPLHSSGLL QPPPPPPPPP ALVPGYNGTS 240
NLSSYSYPSA SYPPQTAVGS GYSPGGAPPP PSAYLPSGIP APTPLPPTTV PGYTYQGHGL 300
TPIAPSALTN SSASSLKRKA FYMAGQGDMD SSYGNYSYGQ QRSTQSLCDR MPDNSISNSN 360
RGNGFDRSAE TSSLAFKPTK QLMSSEQQRK FSSQSSRALT PPSYSTAKNS LGSRSSESFG 420
KYTSPVMSEH GDEHRQLLSH PMQGPGLRAA TSSNHSVDEQ LKNTDTHLID LVTNEIITQG 480
PPVDWNDIAG LDLVKAVIKE EVLWPVLRSD AFSGLTALPR SILLFGPRGT GKTLLGRCIA 540
SQLGATFFKI AGSGLVAKWL GEAEKIIHAS FLVARCRQPS VIFVSDIDML LSSQVSEEHS 600
PVSRMRTEFL MQLDTVLTSA EDQIIVICAT SKPEEIDESL RRYFMKRLLI PLPDSTARHQ 660
IIVQLLSQHN YCLNDKEFAL LVQRTEGFSG LDVAHLCQEA AVGPLHAMPA TDLSAIMPSQ 720
LRPITYQDFE NAFCKIQPSI SQKELDMYVE WNKMFGCSQ 759

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologFIGN102182074A0A452F2S0Capra hircusPredictionMore>>
1:1 orthologFIGN55137Q5HY92Homo sapiensPredictionMore>>
1:1 orthologFign60344Q9ERZ6CPOMus musculusPublicationMore>>
1:1 orthologFIGN470574A0A2I3SNC4Pan troglodytesPredictionMore>>
1:1 orthologFIGNA0A286ZU82Sus scrofaPredictionMore>>
1:1 orthologFIGN100346621A0A5F9C299Oryctolagus cuniculusPredictionMore>>
1:1 orthologFign295649D3ZYS4Rattus norvegicusPredictionMore>>
1:1 orthologfignF1QMW5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016363 nuclear matrix
GO:0005634 nucleus
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0008568 microtubule-severing ATPase activity
GO:0008022 protein C-terminus binding
GO:0031122 cytoplasmic microtubule organization
GO:0010569 regulation of double-strand break repair via homologous recombination

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0067 ATP-binding
KW-0547 Nucleotide-binding
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR003960 ATPase_AAA_CS
IPR027417 P-loop_NTPase
IPR015415 Vps4_C

PROSITE

PROSITE ID PROSITE Term
PS00674 AAA

Pfam

Pfam ID Pfam Term
PF00004 AAA
PF09336 Vps4_C