| Tag | Content |
|---|---|
| Uniprot ID | A0A286ZU82 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000035046 |
| Ensembl nucleotide ID | ENSSSCG00000034262 |
| Gene name | Fidgetin, microtubule severing factor |
| Gene symbol | FIGN |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MISSTSVYGL KMQWTPEHAQ WPEQHFDITS TTRSPAHKVE AYRGHLQRTY QYAWANDDIS 60 ALTASNLLKK YAEKYSGILE GPVDRSVLSN YSDAPSGLVN GRKNESEPWQ PSLNSDAVYP 120 MNCVPDVITA SKAGVSSALP PADVSASIGS SPGVASNLTE PSYSSSTCGS HTVPSLHTGL 180 PSQEYAPGYN GSYLHSTYSS QPAPALPSPH PSPLHSSGLL QPPPPPPPPP ALVPGYNGTS 240 NLSSYSYPSA SYPPQTAVGS GYSPGGAPPP PSAYLPSGIP APTPLPPTTV PGYTYQGHGL 300 TPIAPSALTN SSASSLKRKA FYMAGQGDMD SSYGNYSYGQ QRSTQSLCDR MPDNSISNSN 360 RGNGFDRSAE TSSLAFKPTK QLMSSEQQRK FSSQSSRALT PPSYSTAKNS LGSRSSESFG 420 KYTSPVMSEH GDEHRQLLSH PMQGPGLRAA TSSNHSVDEQ LKNTDTHLID LVTNEIITQG 480 PPVDWNDIAG LDLVKAVIKE EVLWPVLRSD AFSGLTALPR SILLFGPRGT GKTLLGRCIA 540 SQLGATFFKI AGSGLVAKWL GEAEKIIHAS FLVARCRQPS VIFVSDIDML LSSQVSEEHS 600 PVSRMRTEFL MQLDTVLTSA EDQIIVICAT SKPEEIDESL RRYFMKRLLI PLPDSTARHQ 660 IIVQLLSQHN YCLNDKEFAL LVQRTEGFSG LDVAHLCQEA AVGPLHAMPA TDLSAIMPSQ 720 LRPITYQDFE NAFCKIQPSI SQKELDMYVE WNKMFGCSQ 759 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FIGN | 102182074 | A0A452F2S0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | FIGN | 55137 | Q5HY92 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Fign | 60344 | Q9ERZ6 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | FIGN | 470574 | A0A2I3SNC4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | FIGN | A0A286ZU82 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | FIGN | 100346621 | A0A5F9C299 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Fign | 295649 | D3ZYS4 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | fign | F1QMW5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016363 | nuclear matrix |
| GO:0005634 | nucleus |
| GO:0005524 | ATP binding |
| GO:0016887 | ATPase activity |
| GO:0008568 | microtubule-severing ATPase activity |
| GO:0008022 | protein C-terminus binding |
| GO:0031122 | cytoplasmic microtubule organization |
| GO:0010569 | regulation of double-strand break repair via homologous recombination |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00674 | AAA |