Gene: RFNG

Basic information

Tag Content
Uniprot ID A0A2I3RLY5; A0A2J8JFP9;
Entrez ID 747153
Genbank protein ID
Genbank nucleotide ID XM_016930964.1
Ensembl protein ID ENSPTRP00000065703
Ensembl nucleotide ID ENSPTRG00000009787
Gene name Beta-1,3-N-acetylglucosaminyltransferase
Gene symbol RFNG
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSRARGALCR ACLALAAALA ALLLLPLPLP LPRAPAPART PAPAPRAPPS RPAAPSLRPD 60
DVFIAVKTTR KNHGPRLRLL LRTWISRARQ QTFIFTDGDD PELELQGGGR VINTNCSAVR 120
TRQALCCKMS VEYDKFIESG RKWFCHVDDD NYVNARSLLH LLSSFSPSQD VYLGRPSLDH 180
PIEATERVQG GRTVTTVKFW FATGGAGFCL SRGLALKMSP WASLGSFMST AEQVRLPDDC 240
TVGYIVEGLL GARLLHSTLF HSHLENLQRL PPDTLLQQVT LSYGGPENPH NVVNVAGGFS 300
LHQDPTRFKS IHCLLYPDTD WCPRQKQGAP TSR 333

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologRFNG102178013A0A452G5I0Capra hircusPredictionMore>>
1:1 orthologRFNG5986Q9Y644Homo sapiensPredictionMore>>
1:1 orthologRfng19719O09009CPOMus musculusPublicationMore>>
1:1 orthologRFNG747153A0A2I3RLY5Pan troglodytesPredictionMore>>
1:1 orthologRFNGA0A286ZQY8Sus scrofaPredictionMore>>
1:1 orthologRfng60433Q6P6T7Rattus norvegicusPredictionMore>>
1:1 orthologrfng414848F1QXC7Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0030173 integral component of Golgi membrane
GO:0008375 acetylglucosaminyltransferase activity
GO:0046872 metal ion binding
GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
GO:0007389 pattern specification process
GO:0045747 positive regulation of Notch signaling pathway
GO:0032092 positive regulation of protein binding
GO:0036066 protein O-linked fucosylation
GO:0008593 regulation of Notch signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0328 Glycosyltransferase
KW-0333 Golgi apparatus
KW-0464 Manganese
KW-0472 Membrane
KW-0479 Metal-binding
KW-1185 Reference proteome
KW-0808 Transferase

Interpro

InterPro ID InterPro Term
IPR017374 Fringe
IPR003378 Fringe-like

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF02434 Fringe