| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3TCV4 |
| Entrez ID | 453261 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016927806.1 |
| Ensembl protein ID | ENSPTRP00000087083 |
| Ensembl nucleotide ID | ENSPTRG00000006834 |
| Gene name | OCA2 melanosomal transmembrane protein |
| Gene symbol | OCA2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MHLEGRDGRR YPGTPAVELL QTSVPTGLAE LAAGKHRLPR GAGGADPSHS CPSGAAGQSS 60 WAPAGQEFAS FLTKGRSHSS LPQMSSSRSK DSCFTENTPL LRNSLQEKGS RCIPVYHPEF 120 ITAEESWEDS SADWERRYLL SREVSGLSAS ASSEKGDLLD SPHIRLRLSK LRRCVQWLKV 180 TGLFVFVVLC SILFSLYPDQ GKLWQLLALS PLENYSVNLS SHVDSTLLQV DLAGALVASG 240 PSRPGREEHI VVELTQADAL GSRWRRPQQV THNWTVYLNP RRSEHSVMSR TFEVLTRETV 300 SISIRASLQQ TQAVPLLMAH QYLRGSVEAQ VTIATAILAG VYALIIFEIV HRTLAAMLGS 360 LAALAALAVI GDRPSLTHVV EWIDFETLAL LFGMMILVAI FSETGFFDYC AVKAYRLSRG 420 RVWAMIIMLC LIAAVLSAFL DNVTTMLLFT PVTIRLCEVL NLDPRQVLIA EVIFTNIGGA 480 ATAIGDPPNV IIVSNQELRK MGLDFAGFTA HMFIGICLVL LVCFPLLRLL YWNRKLYNKE 540 PSEIVELKHE IHVWRLTAQR ISPASREETA VRRLLLGKVL ALEHLLAQRL HTFHRQISQE 600 DKNWETNIQE LQKKHRISDG ILLAKCLTVL GFAIFMFFLN SFVPGIHLDL GWIAILGAIW 660 LLILADIHDF EIILHRVEWA TLLFFAALFV LMEALAHLHL IEYVGEQTAL LIKMVPEEQR 720 LTAAIVLVVW VSALASSLID NIPFTATMIP VLLNLSHDPE VGLPAPPLMY ALAFGACLGG 780 NGTLIGASAN VVCAGIAEQH GYGFSFMEFF RLGFPMMVVS CTVGMCYLLV AHVVVGWN 838 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | OCA2 | A0A452G2D0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | OCA2 | 4948 | Q04671 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Oca2 | 18431 | Q62052 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | OCA2 | 453261 | A0A2I3TCV4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A287A8S4 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Oca2 | 100365773 | Q4LEV3 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0010008 | endosome membrane |
| GO:0016021 | integral component of membrane |
| GO:0005765 | lysosomal membrane |
| GO:0033162 | melanosome membrane |
| GO:0055085 | transmembrane transport |
| InterPro ID | InterPro Term |
|---|---|
| IPR004680 | Cit_transptr-like_dom |
| Pfam ID | Pfam Term |
|---|---|
| PF03600 | CitMHS |