| Tag | Content |
|---|---|
| Uniprot ID | Q4LEV3 |
| Entrez ID | 100365773 |
| Genbank protein ID | BAE03195.1 |
| Genbank nucleotide ID | NM_001271493.1 |
| Ensembl protein ID | ENSRNOP00000019498 |
| Ensembl nucleotide ID | ENSRNOG00000014465 |
| Gene name | OCA2 melanosomal transmembrane protein |
| Gene symbol | Oca2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MHLENKDIRL ASAMLEVELH QTSALSVPTC PDPGRPLTVK PTASNYELGQ ADPCIPHAGE 60 AAGKSPCVPE HAEFGSFLMK GRTHSPLSQF SSSLKDLSFK EDTPLLWNSP QKKRSQFMPV 120 HHPEFIATED SWESGLTVWE QKCMLGKEVA DLSALASSEK GDLAGGVHLR AQVSKLGCCV 180 RWMKITGLFV FVVLCSILFS LYPDQGKLWQ LLAVSPLENY SVTLSGRADS IILQLDLAGA 240 LMPGGPSGSG KEEHVMVVVT QTDAVGNRWR RPQQVTHNWT VPLNPRSEHV VVSRTFEIVS 300 REAVSISIQA SLQQTRLVPL LLAHQFLGAS VEAQVASAVA ILTGVYTLII FEIVHRTLAA 360 MLGALAALAA LAVVGDRPSL THVVEWIDFE TLALLFGMMI LVAIFSETGF FDYCAVKAYQ 420 LSRGRVWAMI IMLCLMAAIL SAFLDNVTTM LLFTPVTIRL CEVLNLDPRQ VLIAEVIFTN 480 IGGAATAIGD PPNVIIVSNQ ELRKMGLDFA GFTAHMFLGI CLVLLVSFPL LRLLYWNKKL 540 YNKEPSEIVE LKHEIHVWRL TAQRISPASR EETAVRGLLL EKVLALEHLL AQRLHTFHRQ 600 ISQEDKNWET NIQELQRKHR ISDRSLLVKC LTVLGFVISM FFLNSFVPGI HLDLGWIAIL 660 GAIWLLILAD IHDFEIILHR VEWATLLFFA ALFVLMEALT HLHLVEYVGE QTALLIKMVP 720 EDQRFAAAIV LIVWVSALAS SLIDNIPFTA TMIPVLLNLS QDPEISLPAL PLMYALALGA 780 CLGGNGTLIG ASANVVCAGI AEQHGYGFSF MEFFRLGFPM MLMSCTIGMC YLLIAHVVVG 840 WN 842 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | OCA2 | A0A452G2D0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | OCA2 | 4948 | Q04671 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Oca2 | 18431 | Q62052 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | OCA2 | 453261 | A0A2I3TCV4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A287A8S4 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Oca2 | 100365773 | Q4LEV3 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0010008 | endosome membrane |
| GO:0016021 | integral component of membrane |
| GO:0005765 | lysosomal membrane |
| GO:0033162 | melanosome membrane |
| GO:0008283 | cell population proliferation |
| GO:0048066 | developmental pigmentation |
| GO:0042438 | melanin biosynthetic process |
| GO:0030318 | melanocyte differentiation |
| GO:0043473 | pigmentation |
| GO:0007286 | spermatid development |
| GO:0055085 | transmembrane transport |
| InterPro ID | InterPro Term |
|---|---|
| IPR004680 | Cit_transptr-like_dom |
| Pfam ID | Pfam Term |
|---|---|
| PF03600 | CitMHS |