Gene: DCAF7

Basic information

Tag Content
Uniprot ID A0A452DQT9
Entrez ID 102172756
Genbank protein ID
Genbank nucleotide ID XM_005693979.3
Ensembl protein ID ENSCHIP00000002141
Ensembl nucleotide ID ENSCHIG00000004757
Gene name WD_REPEATS_REGION domain-containing protein
Gene symbol DCAF7
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSLHGKRKEI YKYEAPWTVY AMNWSVRPDK RFRLALGSFV EEYNNKVQLV GLDEESSEFI 60
CRNTFDHPYP TTKLMWIPDT KGVYPDLLAT SGDYLRVWRV GETETRLECL LNNNKNSDFC 120
APLTSFDWNE VDPYLLGTSS IDTTCTIWGL ETGQVLGRVN LVSGHVKTQL IAHDKEVYDI 180
AFSRAGGGRD MFASVGADGS VRMFDLRHLE HSTIIYEDPQ HHPLLRLCWN KQDPNYLATM 240
AMDGMEVVIL DVRVPCTPVA RLNNHRACVN GIAWAPHSSC HICTAADDHQ ALIWDIQQMP 300
RAIEDPILAY TAEGEINNVQ WASTQPDWIA ICYNNCLEIL RV 342

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologDCAF7516678Q32L87Bos taurusPredictionMore>>
1:1 orthologDCAF7100856670E2REP1Canis lupus familiarisPredictionMore>>
1:1 orthologDCAF7102172756A0A452DQT9Capra hircusPredictionMore>>
1:1 orthologDCAF710238P61962Homo sapiensPublicationMore>>
1:1 orthologDcaf771833P61963Mus musculusPredictionMore>>
1:1 orthologDCAF7454780K7B4V7Pan troglodytesPredictionMore>>
1:1 orthologDCAF7100347842G1TAE4Oryctolagus cuniculusPredictionMore>>
1:1 orthologDcaf7303602B2RZ68Rattus norvegicusPredictionMore>>
1:1 orthologdcaf7337565Q7T3E0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
GO:0005829 cytosol
GO:0016604 nuclear body
GO:0016363 nuclear matrix

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0853 WD repeat

Interpro

InterPro ID InterPro Term
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf

PROSITE

PROSITE ID PROSITE Term
PS00678 WD_REPEATS_1
PS50082 WD_REPEATS_2
PS50294 WD_REPEATS_REGION

Pfam

Pfam ID Pfam Term
PF00400 WD40