| Tag | Content |
|---|---|
| Uniprot ID | A0A452E234 |
| Entrez ID | 102177400 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018047439.1 |
| Ensembl protein ID | ENSCHIP00000006072 |
| Ensembl nucleotide ID | ENSCHIG00000009890 |
| Gene name | Uncharacterized protein |
| Gene symbol | CYP51A1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MVMLDLLQAG GSVLEQAMEQ VTGGNLPSML LIACAFTLSL VYLLRLAVGH LAPPLPAGAK 60 SPPYIVSPIP FLGHAIAFGK SPIEFLEDAY EKYGPVFSFT MVGKTFTYLL GSEAAALLFN 120 SKNEDLNAED VYSRLTTPVF GKGVAYDVPN TVFLEQKKML KSGLNIAHFR QHVSIIEKET 180 KDYFRSWGES GEKNLFEALS ELIILTASHC LHGKEIRGQL NEKVAQLYAD LDGGFSHAAW 240 LLPGWLPLPS FRRRDRAHRE IKNIFYKAIQ KRRESGEKID DILQTLLEST YKDGRPLTDD 300 EIAGMLIGLL LAGQHTSSTT SAWMGFFLAR DKTLQEKCFS EQKTVCGENL PPLSYDQLKD 360 LNLLDRCIKE TLRLRPPIMT MMRLAKTPQT VAGYTIPPGH QVCVSPTVNQ RLKDSWVERL 420 DFNPDRYLED SLASGEKFAY VPFGAGRHRC IGENFAYVQI KTIWSTMLRL YEFDLIDGYF 480 PTVNYTTMIH TPENPVIRYK RRSK 504 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CYP51A1 | 505060 | Q4PJW3 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | CYP51A1 | 102177400 | A0A452E234 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | CYP51A1 | 1595 | A0A0C4DFL7 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Cyp51a1 | 13121 | Q8K0C4 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | CYP51A1 | 403334 | O46420 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Cyp51a1 | 25427 | Q64654 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | cyp51 | 414331 | Q1JPY5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005783 | endoplasmic reticulum |
| GO:0016021 | integral component of membrane |
| GO:0020037 | heme binding |
| GO:0005506 | iron ion binding |
| GO:0004497 | monooxygenase activity |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00086 | CYTOCHROME_P450 |
| Pfam ID | Pfam Term |
|---|---|
| PF00067 | p450 |