| Tag | Content |
|---|---|
| Uniprot ID | A0A452EUB6 |
| Entrez ID | 102170921 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018038231.1 |
| Ensembl protein ID | ENSCHIP00000015521 |
| Ensembl nucleotide ID | ENSCHIG00000016131 |
| Gene name | Protein Wnt |
| Gene symbol | WNT5A |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Ligand for members of the frizzled family of seven transmembrane receptors. |
| Sequence | MKKSIGILSP GVAWGTAARA MSSKFFLMAL AIFLSFAQVV IEANSWWSLG MNNPVQMSEV 60 YIIGAQPLCS QLAGLSQGQK KLCHLYQDHM QYIGEGAKTG IKECQYQFRH RRWNCSTVDN 120 TSVFGRVMQI GSRETAFTYA VSAAGVVNAM SRACREGELS TCGCSRAARP KDLPRDWLWG 180 GCGDNIDYGY RFAKEFVDAR ERERIHAKGS YESARILMNL HNNEAGRRTV YSLADVACKC 240 HGVSGSCSLK TCWLQLADFR KVGDALKEKY DSAAAMRLNS RGKLVQVNSR FNSPTTQDLV 300 YIDPSPDYCV RNESTGSLGT QGRLCNKTSE GMDGCELMCC GRGYDQFKMV QTERCHCKFH 360 WCCYVKCKKC TQVVDQFVCK |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WNT5A | 530005 | E1BDG5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | WNT5A | 484721 | J9P5H0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | WNT5A | 102170921 | A0A452EUB6 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | WNT5A | 7474 | P41221 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Wnt5a | 22418 | P22725 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | WNT5A | 100627056 | A0A287A1J0 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Wnt5a | 64566 | F2Z3U1 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005576 | extracellular region |
| GO:0005102 | signaling receptor binding |
| GO:0007275 | multicellular organism development |
| GO:0016055 | Wnt signaling pathway |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00246 | WNT1 |
| Pfam ID | Pfam Term |
|---|---|
| PF00110 | wnt |