Gene: TBX10

Basic information

Tag Content
Uniprot ID A0A452G9N7
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000033354
Ensembl nucleotide ID ENSCHIG00000026949
Gene name Uncharacterized protein
Gene symbol TBX10
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
AFLSASLGVF APSETYTLPK TSSSWEPQPD SMLPSGPSTG STGAPAVAEP TVQGPKNPHV 60
SSVTVQLEMK ALWEEFNQLG TEMIVTKAGR RMFPTFQVKI LGMDSLADYA LLMDFVPLDD 120
KRYRYAFHSS AWLVAGKADP ATPGRVHFHP DSPAKGAQWM RQIVSFDKLK LTNNLLDENG 180
HIILNSMHRY QPRFHVVFVD PRKDSERYAQ ENFKSFIFAE TQFTAVTAYQ NHRITQLKIA 240
SNPFAKGFRE NHDPWPGLPT MTPAPIPACP TSSVPTRSRS SLGPHLLKGS TERKKDPNKA 300
FTSRIPARLH HQLLAPPEAL LAPATYPPLA YQGLYTGASS PVRPRARPTP YPLPNIQADR 360
DQGGLPLPAG LGLLSPTAMC LGPGQDPQ 388

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTBX10A0A452G9N7Capra hircusPredictionMore>>
1:1 orthologTBX10347853O75333Homo sapiensPredictionMore>>
1:1 orthologTbx10109575Q810F8CLPMus musculusPublicationMore>>
1:1 orthologTBX10H2Q495Pan troglodytesPredictionMore>>
1:1 orthologTbx10688822D3ZAQ3Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0539 Nucleus
KW-1185 Reference proteome
KW-0804 Transcription
KW-0805 Transcription regulation

Interpro

InterPro ID InterPro Term
IPR008967 p53-like_TF_DNA-bd
IPR036960 T-box_sf
IPR001699 TF_T-box
IPR018186 TF_T-box_CS

PROSITE

PROSITE ID PROSITE Term
PS01283 TBOX_1
PS01264 TBOX_2
PS50252 TBOX_3

Pfam

Pfam ID Pfam Term
PF00907 T-box