| Tag | Content |
|---|---|
| Uniprot ID | D3ZAQ3 |
| Entrez ID | 688822 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_017590275.1; XM_006223597.3; XM_006230921.3; XM_017604253.1; |
| Ensembl protein ID | ENSRNOP00000024129 |
| Ensembl nucleotide ID | ENSRNOG00000017944 |
| Gene name | T-box transcription factor 10 |
| Gene symbol | Tbx10 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSTEAYAMAE PTGQGPKNPR VSSVMVQLEM KPLWEEFNQL GTEMIVTKAG RRMFPTFQVK 60 IVGMDTLADY ALLMDFIPLD DKRYRYAFHS SAWLVAGKAD PATPGRVHFH PDSPAKGAQW 120 MRQIVSFDKL KLTNNLMDDN GHIILNSMHR YQPRFHVVFV DPRKDSARYA QENFKSFVFM 180 ETQFTAVTAY QNHRITQLKI ASNPFAKGFR EADPDSWPAT PRPLLSIPAR SRSSLGPCLL 240 KGSAEREKDT SGTSASRPRT PTQTHHQLLP APDVLLAPAT YRPLPYQNLY PGSPSHAGTS 300 RARLAPYPLP NISTAGNQED PTFAAGLGLL PTSALCLVPN QDSK 344 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TBX10 | A0A452G9N7 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | TBX10 | 347853 | O75333 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Tbx10 | 109575 | Q810F8 | CLP | Mus musculus | Publication | More>> | |
| 1:1 ortholog | TBX10 | H2Q495 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Tbx10 | 688822 | D3ZAQ3 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0001102 | RNA polymerase II activating transcription factor binding |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0001708 | cell fate specification |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Pfam ID | Pfam Term |
|---|---|
| PF00907 | T-box |