| Tag | Content |
|---|---|
| Uniprot ID | A2BDM6 |
| Entrez ID | 58150 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_131626.3 |
| Ensembl protein ID | ENSDARP00000022921 |
| Ensembl nucleotide ID | ENSDARG00000008305 |
| Gene name | Heart- and neural crest derivatives-expressed protein 2 |
| Gene symbol | hand2 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSLVGGFPHH PVMHHDGYSF AAASRCHEEP PYFHGWLISH PEMSPPDYTM APSYSPEYST 60 GAPGLDHSHY GGVPGAGAVG MGPRTVKRRP TANRKERRRT QSINSAFAEL RECIPNVPAD 120 TKLSKIKTLR LATSYIAYLM DILDKDEQNG ETEAFKAEFK KTDAKEERRK KEMNDVLKSS 180 GSSNDKKTKG RTGWPQHVWA LELKQ 205 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | HAND2 | 102171973 | A0A452ECE7 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | HAND2 | 9464 | P61296 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Hand2 | 15111 | Q61039 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | HAND2 | 741581 | H2R7W4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | HAND2 | A0A287BKC6 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Hand2 | A0A0G2K7Q4 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | hand2 | 58150 | A2BDM6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0046983 | protein dimerization activity |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50888 | BHLH |
| Pfam ID | Pfam Term |
|---|---|
| PF00010 | HLH |