Gene: HSD17B7

Basic information

Tag Content
Uniprot ID A4FUD2
Entrez ID 505212
Genbank protein ID AAI14717.1
Genbank nucleotide ID NM_001083375.1
Ensembl protein ID ENSBTAP00000007841
Ensembl nucleotide ID ENSBTAG00000005976
Gene name HSD17B7 protein
Gene symbol HSD17B7
Organism Bos taurus
NCBI taxa ID 9913
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MRKVVLITGA SSGVGLALCR RLLEEDDALH LCLACRNMSK AEAVRTSLLA SHPAAEVSIV 60
QVDVSSLPSV FQATKELKQR FQRLDYVYLN AGIMPNPQLN IKALFRGLFS RKVIHMFSTA 120
EGLLTQNDKI TPDGLQEVFE TNVFGHFILI QELESLLCHS ESPSQLIWTS SRNAKKSNFS 180
FEDVQHSKGQ EPYSSSKYAI DLLSVALNRH FNHQGLYSSV VCPGTMLTNL TYGILPPFVW 240
MLIMPIIWLL RFFANAFTLT PHNGTEALVW LFHQKPESLN PLVKYLSATT GFGSNYVTSK 300
KMDLDEDTAE KFYQKLLKLE KEIRVTIQKT NNQN 334

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologHSD17B7505212A4FUD2Bos taurusPredictionMore>>
1:1 orthologHSD17B7609364E2RNT4Canis lupus familiarisPredictionMore>>
1:1 orthologHSD17B7102179058A0A452DSV0Capra hircusPredictionMore>>
1:1 orthologHSD17B751478P56937Homo sapiensPredictionMore>>
1:1 orthologHsd17b715490O88736CPOMus musculusPublicationMore>>
1:1 orthologHSD17B7H2Q1T6Pan troglodytesPredictionMore>>
1:1 orthologHSD17B7F1S213Sus scrofaPredictionMore>>
1:1 orthologHsd17b729540Q62904Rattus norvegicusPredictionMore>>
1:1 orthologhsd17b7768185Q08BC5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
GO:0000253 3-keto sterol reductase activity
GO:0030154 cell differentiation
GO:0006695 cholesterol biosynthetic process
GO:0048706 embryonic skeletal system development
GO:0007399 nervous system development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR042829 HSD17B7
IPR036291 NAD(P)-bd_dom_sf
IPR002347 SDR_fam

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF00106 adh_short