| Tag | Content |
|---|---|
| Uniprot ID | A6H7B8 |
| Entrez ID | 540520 |
| Genbank protein ID | AAI46187.1 |
| Genbank nucleotide ID | XM_010812668.2; XM_015474767.1; NM_001099111.1; |
| Ensembl protein ID | |
| Ensembl nucleotide ID | |
| Gene name | Post-GPI attachment to proteins factor 2 |
| Gene symbol | PGAP2 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface (By similarity). |
| Sequence | MYQVPLPLDR DGTLVRLRFT LVALVTVCCP LVAFLFCVLW SLLFHFKETT ATHCGVPNYL 60 PSVSSAIGGE VPQRYVWRFC IGLHSAPRFL VAFAYWNHYL SCTSPCAGYR PLCRLNFGLN 120 VVENVALLVL TYVSSSEDFT IHENAFIVFI ASSLSHMLLT CILWRLTKKH TVSQEDRKSY 180 NWKQRLFIIN FVSFFTALAV YFRHNMYCEA GVYTIFAILE YTVVLTNMAF HMTAWWDFGN 240 KELLITSQPE EKRF 254 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PGAP2 | 540520 | A6H7B8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PGAP2 | 102190338 | A0A452GA35 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PGAP2 | 100053037 | A0A3Q2HNJ2 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | PGAP2 | 27315 | Q9UHJ9 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pgap2 | 233575 | Q3TQR0 | CPO,CLP,CLO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PGAP2 | 743877 | K7AX68 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | PGAP2 | A0A286ZK90 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Pgap2 | D4ACY7 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | pgap2 | 541417 | G1K2N7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0000139 | Golgi membrane |
| GO:0016021 | integral component of membrane |
| GO:0006506 | GPI anchor biosynthetic process |
| Pfam ID | Pfam Term |
|---|---|
| PF10277 | Frag1 |