| Tag | Content |
|---|---|
| Uniprot ID | D3ZRA8 |
| Entrez ID | 500574 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001191984.1 |
| Ensembl protein ID | ENSRNOP00000025488 |
| Ensembl nucleotide ID | ENSRNOG00000018739 |
| Gene name | Paired box 7 |
| Gene symbol | Pax7 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAALPGAVPR MMRPGPGQNY PRTGFPLEVS TPLGQGRVNQ LGGVFINGRP LPNHIRHKIV 60 EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA IGGSKPRQVA TPDVEKKIEE 120 YKRENPGMFS WEIRDRLLKD GHCDRSTVPS VSSISRVLRI KFGKKEDDEE GDKKEEDGEK 180 KAKHSIDGIL GDKGNRLDEG SDVESEPDLP LKRKQRRSRT TFTAEQLEEL EKAFERTHYP 240 DIYTREELAQ RTKLTEARVQ VWFSNRRARW RKQAGANQLA AFNHLLPGGF PPTGMPTLPP 300 YQLPDSAYPT TTVSQDGGST VHRPQPLPPS TMHQGGLAAA AAAADSSSAY GARHSFSSYS 360 DSFMNPGAPS NHMNPVSNGL SPQVMSILSN PSAVPPQPQA DFSISPLHGG LDSASSISAS 420 CSQRADSIKP GDSLPTSQSY CPPTYSTTGY SVDPVAGYQY SQYGQTAVDY LAKNVSLSTQ 480 RRMKLGEHSA VLGLLPVETG QAY 503 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PAX7 | E1BKL5 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | PAX7 | 102172220 | A0A452FU61 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PAX7 | 5081 | P23759 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Pax7 | 18509 | P47239 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PAX7 | 456574 | H2PY64 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Pax7 | A0A1S6QCC5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Pax7 | 500574 | D3ZRA8 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pax7a | B3DJI1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0043565 | sequence-specific DNA binding |
| GO:0051216 | cartilage development |
| GO:0006338 | chromatin remodeling |
| GO:0021904 | dorsal/ventral neural tube patterning |
| GO:0048706 | embryonic skeletal system development |
| GO:0060415 | muscle tissue morphogenesis |
| GO:0048663 | neuron fate commitment |
| GO:0031062 | positive regulation of histone methylation |
| GO:2000288 | positive regulation of myoblast proliferation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0010453 | regulation of cell fate commitment |
| GO:0051101 | regulation of DNA binding |
| GO:0010468 | regulation of gene expression |
| GO:0014813 | skeletal muscle satellite cell commitment |
| GO:0007519 | skeletal muscle tissue development |
| GO:0043403 | skeletal muscle tissue regeneration |
| GO:0021527 | spinal cord association neuron differentiation |