| Tag | Content |
|---|---|
| Uniprot ID | H2PY64; A0A2J8KEK9; K7CAU3; |
| Entrez ID | 456574 |
| Genbank protein ID | JAA39676.1 |
| Genbank nucleotide ID | XM_001157066.4 |
| Ensembl protein ID | ENSPTRP00000000452 |
| Ensembl nucleotide ID | ENSPTRG00000000253 |
| Gene name | Paired box 7 |
| Gene symbol | PAX7 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAALPGTVPR MMRPAPGQNY PRTGFPLEVS TPLGQGRVNQ LGGVFINGRP LPNHIRHKIV 60 EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA IGGSKPRQVA TPDVEKKIEE 120 YKRENPGMFS WEIRDRLLKD GHCDRSTVPS GLVSSISRVL RIKFGKKEEE DEADKKEDDG 180 EKKAKHSIDG ILGDKGNRLD EGSDVESEPD LPLKRKQRRS RTTFTAEQLE ELEKAFERTH 240 YPDIYTREEL AQRTKLTEAR VQVWFSNRRA RWRKQAGANQ LAAFNHLLPG GFPPTGMPTL 300 PPYQLPDSTY PTTTISQDGG STVHRPQPLP PSTMHQGGLA AAAAAADTSS AYGARHSFSS 360 YSDSFMNPAA PSNHMNPVSN GLSPQVMSIL GNPSAVPPQP QADFSISPLH GGLDSATSIS 420 ASCSQRADSI KPGDSLPTSQ AYCPPTYSTT GYSVDPVAGY QYGQYGQTAV DYLAKNVSLS 480 TQRRMKLGEH SAVLGLLPVE TGQAY 505 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PAX7 | E1BKL5 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | PAX7 | 102172220 | A0A452FU61 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PAX7 | 5081 | P23759 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Pax7 | 18509 | P47239 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PAX7 | 456574 | H2PY64 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Pax7 | A0A1S6QCC5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Pax7 | 500574 | D3ZRA8 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pax7a | B3DJI1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0043565 | sequence-specific DNA binding |
| GO:0051216 | cartilage development |
| GO:0006338 | chromatin remodeling |
| GO:0021904 | dorsal/ventral neural tube patterning |
| GO:0048706 | embryonic skeletal system development |
| GO:0060415 | muscle tissue morphogenesis |
| GO:0048663 | neuron fate commitment |
| GO:0031062 | positive regulation of histone methylation |
| GO:2000288 | positive regulation of myoblast proliferation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0010453 | regulation of cell fate commitment |
| GO:0051101 | regulation of DNA binding |
| GO:0014813 | skeletal muscle satellite cell commitment |
| GO:0043403 | skeletal muscle tissue regeneration |
| GO:0021527 | spinal cord association neuron differentiation |