| Tag | Content |
|---|---|
| Uniprot ID | D3ZWN3 |
| Entrez ID | 289711 |
| Genbank protein ID | EDM00024.1 |
| Genbank nucleotide ID | NM_001106012.1 |
| Ensembl protein ID | ENSRNOP00000009914 |
| Ensembl nucleotide ID | ENSRNOG00000007025 |
| Gene name | Ellis van Creveld syndrome 2 homolog (Human) (Predicted) |
| Gene symbol | Evc2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGATGLTGTG GQATWVLAGN ILAAALVLGV GPCALPPSFP ALGPGSPSPP DPVGPRASSQ 60 HSDISRDAQG PSENGVIFQK CSLVSGQSES QTMHVQLSVN NTRTPMSANL SDLLVLDDIT 120 GLTVKESPGN VTQEGIQTFR KRFLQVGECY SVSYMASLDP TALGPGESLD LPAQLIFQRP 180 SQNRTQLRAR FTITVEEKIM VLPNHGLHTA GFIAAFLISF LLTLAALFFL ARGRCLQGSM 240 LLRCRVQHPE NKLEPSPFTS ANGVSQDLSL NDQLVAILTS EEPGSMLQAL EELEIATLNQ 300 ADADLEACRN QISKDIIALL MKNLISGGHL SLQTERKMAA AFKKQFLLLE NEIQEEYERK 360 MLALTAECDL EVRKKTENQY QREMVAMEEA EEVLKRVSER SAAECSSLLR TLHGLEQEDL 420 QRSLTLQQAE DFAQAHRQLA VFQRNELHSI VYTQIQSAVA KGELRPEVAK MLLQDYSKTQ 480 ESIEELMDFF QATKRYHLSK RFGHREYLVQ RLQAMETRVQ GLLSTAATQL TSLIHKHERA 540 GYLDEDQMEM LLERAQTETF SIKQKLDNDL KQEKKRLHQK LITKRRRELL QKHKEQQKEQ 600 VSLGEASSTA EDAIQYLQQW RSVMAEHTTA LEELQERLDQ AALDDLRVLT VSLSEKATEE 660 LRRLQSTAMT QELLKRSAPW LFLQQILEEH SRESAARTAQ LEAEERERGQ ELVQGVRQRL 720 QQDAPEACTE EQAELRHWEH LVFTKLCSAA ISLSEEDLLR VRQEAQGCFT QLDRSLALPR 780 VRARVLQQQM QMTWREAEFR KLDQALAVPE LQSKSRKLRS KGRGKADLLK KNLEDKIRLF 840 EERAPEDLAD QVRGELLQER VQRLEAQEAH FAESLVALQF QKVARAAETL SVYTALLSIQ 900 DLLLGELSES ETLTKSACVQ ILESHRPELL ELERMLEDRL VQQEEAEQRR VLESRQRWAA 960 DGPALGEPEE IDPERQVSAV LRQALNKGQK LLEQYQQRVR EEQQNGAVLE DSLESMETDT 1020 MASLCSQGLR LVSYLSRMTM VPGGTLLRLL SVVLPAASQP QLLALLDAVS EKHSDHTAEN 1080 ESGGEQAQAE QGKRRKHQSW WKALDSRFRA DLVSQGLERM LWARRKKESI LKKRYVPVQE 1140 RVVFPGKGSW PHLSLEPIGE LAPIPITGLD TMDILNTGEK IFVFRSPKEP EISLRVPPRR 1200 KKNFLNAKAA SRALGLD 1217 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EVC2 | F1PZ45 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | EVC2 | A0A452ELR2 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | EVC2 | 132884 | Q86UK5 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Evc2 | 68525 | Q8K1G2 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | EVC2 | 461676 | A0A2I3S1F9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Evc2 | 289711 | D3ZWN3 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0060170 | ciliary membrane |
| GO:0005929 | cilium |
| GO:0016021 | integral component of membrane |
| GO:0005634 | nucleus |
| GO:0098797 | plasma membrane protein complex |
| GO:0007224 | smoothened signaling pathway |
| Pfam ID | Pfam Term |
|---|---|
| PF12297 | EVC2_like |