Gene: Disp1

Basic information

Tag Content
Uniprot ID D3ZWU2
Entrez ID 289338
Genbank protein ID EDL94886.1; EDL94887.1; EDL94885.1;
Genbank nucleotide ID XM_008769827.2; XM_006250381.3; XM_017598736.1; XM_017598735.1; XM_017598737.1; NM_001105983.1; XM_006250384.3; XM_006250383.3;
Ensembl protein ID ENSRNOP00000004834
Ensembl nucleotide ID ENSRNOG00000003635
Gene name Dispatched RND transporter family member 1
Gene symbol Disp1
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAVISGSDSV LLSNGSISTS TTNPSPLTPS DGDLTAQQLA PRETPRTKAS PNGCLQLNGT 60
VKSSFLPLDN QRTPQTALCC HPCPYHHPVT SHTSHQECHP EAGLAASSAL TSGCIQPHSE 120
YSASLCPNHS PVYQAAHCRQ PSPSLCLHHP WPDHFQHQPV RQHLAIIGPS RPFRFPRSYA 180
ALLADWPVVV LGLCTLLIVV CALVGVLVPE LPDFSDPLLG FEPRGTAIGQ RLVTWNNMMK 240
NTGYKATLAN YPYKYAEEQA KSRRDDRWSG DHHERERREV DWNFQKDSFF CDVPSDGYSR 300
VVFASAGGET LWNLPAIKSM CDVDNSRIRS HPQFSDLCQR TTAVSCCPSW TLGNYIAILN 360
NRSSCQKIVE RDVSHTLKLL RTCAKHYQNG TLGPDCWDKA ARRKDQLKCT NVPRKCTKYN 420
AVYQILHYLV DKDFMTSKTA DYAVPALKYS MLFSPTEKGE SMMNIYLDNF ENWNSSDGIT 480
TVTGIEFGIK HSLFQDYLLM DTVYPAIAIA IVLLIMCVYT KSVFITLMTM FAIISSLIVS 540
YFLYRVVFNF EFFPFMNLTA LIILVGIGAD DAFVLCDVWN YTKSDKPRAE TSEAVSVTLQ 600
HAALSMFVTS FTTAAAFYAN YVSNITAIRC FGVYAGTAIL VNYVLMVTWL PAVIVLHERY 660
LLNIFTCFRK PQPQAYHKSC WTVLCRKGRK ALFAISEASR IFFEKVLPCI VIKFRYLWLV 720
WFLALTVGGA YIVCINPKMK LPSLELSEFQ VFRSSHPFER YDAEFKKLFM FERVHHGEEL 780
HMPITVIWGV SPEDSGDPLN PKSKGELTLD STFNIASPAS QAWILHFCQK LRNQTFFHQT 840
EQQDFTSCFI ETFKQWMENQ DCDEPALYPC CSHCSFPYKQ EVFELCIKKA IMELDRSTGY 900
HLNNKTPGPR FDINDTIRAV VLEFQSTFLF TLAYEKMQQF YKEVDSWISH ELSSAPEGLS 960
HGWFVSNLEF YDLQDSLSDG TLIAMGLSVA VAFSVMLLTT CNIIISLYAI ASIAGTIFVT 1020
VGSLVLLGWE LNVLESVTIS VAVGLSVDFA VHYGVAYRLA PDPDREGKVI FSLGRMGSAI 1080
AVAALTTFVA GAMMMPSTVL AYTQLGTFMM LVMCVSWAFA TFFFQCLCRC LGPQGTCGQI 1140
PLPKKLQCSA FSHTSAARPG GRAPGKATNA YSVDARGQKS ELEHELYELQ PLGSHSCTSS 1200
DMTAYEGPCI CSEFFNGQAK NLRMPMSAAY SSELTKSPRS EPGSALLQPC LEQDTMCHFS 1260
LNPRCNCPNA YTHRKYGLPE IHCQQMGDSL CHKCASTAGS FVQIQNAAAP LKATHHAAEG 1320
LLHPVQHMLP PGMQNSQSRN FFLHPVQHFQ AQESLGPTST RGRENTDERP PRTAEPPPAG 1380
ASRSSESFQR ACCNPENNQR RLCKSRDSGD TEGSGGTETK VCGLANQTDK VEKEVKPSLL 1440
QTDEIVNSEQ LNHDEPKLIF SHLIREAGCR PCPDRPQGCR SLRLKCGSTD CQAPDLEANV 1500
PAVPTHSDLS VSGESLLIKT LQ 1522

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologDISP1A0A452EVU7Capra hircusPredictionMore>>
1:1 orthologDISP184976Q96F81Homo sapiensPredictionMore>>
1:1 orthologDisp168897Q3TDN0CPOE13.0, E14.5Mus musculusPublicationMore>>
1:1 orthologDISP1457761A0A2I3SG78Pan troglodytesPredictionMore>>
1:1 orthologDISP1100350276G1SQY2Oryctolagus cuniculusPredictionMore>>
1:1 orthologDisp1289338D3ZWU2Rattus norvegicusPredictionMore>>
1:1 orthologdisp1619201F1QHY7Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane
GO:1904680 peptide transmembrane transporter activity
GO:0042886 amide transport
GO:0007368 determination of left/right symmetry
GO:0060539 diaphragm development
GO:0009953 dorsal/ventral pattern formation
GO:0009880 embryonic pattern specification
GO:0007225 patched ligand maturation
GO:0015833 peptide transport
GO:0055085 transmembrane transport

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR003392 Ptc/Disp
IPR000731 SSD

PROSITE

PROSITE ID PROSITE Term
PS50156 SSD

Pfam

Pfam ID Pfam Term
PF02460 Patched