Gene: disp1

Basic information

Tag Content
Uniprot ID F1QHY7; F1RAG1;
Entrez ID 619201
Genbank protein ID
Genbank nucleotide ID XM_017352524.1; XM_017352523.1;
Ensembl protein ID ENSDARP00000090260; ENSDARP00000065230;
Ensembl nucleotide ID ENSDARG00000044417
Gene name Protein dispatched homolog 1
Gene symbol disp1
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MALSEDFTEL QTLSNGRSSS IFPTTNTPVD PEEEEEQSVS ACTQPNEHTQ MMQTGQNGGL 60
KSTRLSSSSS SSSQLTDAQR LAVLLPNALP PGFCVCCSLC CNGNQQDCAL FQSAVPSAAL 120
HMGSCCVQGV PCFCMQHHWP EHLQNQPNMA TLSPPRPFRF PKSYAELIAD WPVVVLGICT 180
VLIVVCALVG ILVPDLPDFS NPLQGFEPRG TAIGQRLVTW NNMVKNTGYK ATLANYPFKY 240
ADEQAKSHQD DRWSKDHYDR KKRQAEWDFS KDSFFCDVPG DSYSRIVFAS AEGKNLWNIQ 300
AIKSMCNFDN TRVRSHPQYL DLCQRTTAAS CCPSWTLGNY IAVLTNKSSC QKITERDVSH 360
TLNILRSCAK FYHNGTLGPE CWDMTTRKKD LKCGNLPRKC TKYNAVYQIF HFLVDKDFLN 420
PKNTDYLPPN LKYSMLFAPT EKGETMMNIY LDNFENRNSS DGITTITGIE FGIKHSLFQD 480
YLLTDTMYPA IAIVIVLVVM CVYTRSMFIT LMTMFAIISS LIVSYFLYRV VFNFDFFPFM 540
NLTALIILVG IGADDAFVLC DVWNYTKFDK PNSELSETVS ITLQHAALSM FVTSFTTAAA 600
FYANYVSNIT AIRCFGVYAG TAILVNYILM VTWLPAVVVL HERYLVNLLT CSRTQNHQSQ 660
GAATFWTSLC QVVNKCLFSI SEASRIFFEK VLPCVVIKLR YLWLLWFLAL TVGGAYVVCV 720
NPKMKLPSLE LSEFQVFRSS HPFERYDAEY KKLFMFERVN HGEDLHMPIT IIWGVTPIDS 780
GDPLNPKNKG KLTLDTTFNI ASPASQVWIL NFCQKLRNQS FVYQSEEQDF TSCFMETFKQ 840
WMENQDCEEA SVYPCCSQST FPYRQDVFEL CIKRAIMELD RSTIYHLDSK TPGPRFDIND 900
TIRAIVLEFQ STYHFTLAYE KMHQFYREVD TWIQEELRDA PEGLSYGWFV SNLEFYDLQD 960
SLSDGTLIAM ALSVVVAFSV MLLTTWNIII SLYAIISIAG TIFVTVGSLV LLGWELNVLE 1020
SVTISVAVGL SVDFAVHYGV AYRLAPEPDR EGKVVFSLSR MGSAIAMAAL TTFVAGAMMM 1080
PSTVLAYTQL GTFLMLIMCI SWAFATFFFQ CMCRLLGPQG TCGQIPLPKK LQCAERTSEN 1140
QSTVNNQGKA GACYTTKHEH YELEPLAANV RNEGKASDEE QEACTQLQNN ITSLHDDATL 1200
CASHEEPKHE FENGVQATEH SHLHQYAFNT RCTCENSMHQ YIRERQRTAC HPCGQSRETQ 1260
CATKQSNHLP ACLNRDMIHA PTNSGHFQHC TPSQISRPAA HRCFSGGCGM HAMHISQQQT 1320
ETESYISACV PSSSPPESQN RPAHIQFPDV QRCSSPDTTG VCTLNHDTQN AGELAINSQS 1380
PQKIPWNHLK TKANGTCVLQ DCREVVPEDS IGCRVDKEKT VSPKKFNCFK KNVKAKCNSV 1440
EFHKTRTSVP TIAINSKASS ESLC 1464

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologDISP1A0A452EVU7Capra hircusPredictionMore>>
1:1 orthologDISP184976Q96F81Homo sapiensPredictionMore>>
1:1 orthologDisp168897Q3TDN0CPOE13.0, E14.5Mus musculusPublicationMore>>
1:1 orthologDISP1457761A0A2I3SG78Pan troglodytesPredictionMore>>
1:1 orthologDISP1100350276G1SQY2Oryctolagus cuniculusPredictionMore>>
1:1 orthologDisp1289338D3ZWU2Rattus norvegicusPredictionMore>>
1:1 orthologdisp1619201F1QHY7Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR003392 Ptc/Disp
IPR000731 SSD

PROSITE

PROSITE ID PROSITE Term
PS50156 SSD

Pfam

Pfam ID Pfam Term
PF02460 Patched