| Tag | Content |
|---|---|
| Uniprot ID | D4AAY7 |
| Entrez ID | 363464 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_008773179.2; XM_006256875.2; XM_006256873.3; XM_006256876.1; XM_008773181.1; XM_008773178.1; XM_006256870.2; XM_008773176.2; XM_008773177.1; XM_008773180.1; |
| Ensembl protein ID | ENSRNOP00000045342 |
| Ensembl nucleotide ID | ENSRNOG00000003554 |
| Gene name | Phosphatidylinositol glycan anchor biosynthesis, class A |
| Gene symbol | Piga |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MANRRGGGQG QPPSVSPSPG SSGSLSTDRT CTHNICMVSD FFYPNMGGVE SHIYQLSQCL 60 IERGHKVITV THAYGNRKGV RYLTNGLKVY YLPLRVMYNQ STATTLFHSL PLLRYIFVRE 120 RITIIHSHSS FSAMAHDALF HAKTMGLQTV FTDHSLFGFA DVSSVLTNKL LTVSLCDTNH 180 IICVSYTSKE NTVLRAALNP EIVSVIPNAV DPTDFTPEPF RRHDSVITVV VVSRLVYRKG 240 TDLLSGIIPE LCQKYQELNF LIGGEGPKRI ILEEVRERYQ LHDRVQLLGA LEHKDVRNVL 300 VQGHIFLNTS LTEAFCMAIV EAASCGLQVV STKVGGIPEV LPENLIILCE PSVKSLCEGL 360 EKAIFQVKSG TLPAPENIHN VVKTFYTWRN VAERTEKVYE RVSKESVLPM HKRLDRLISH 420 CGPVTGYIFA LLAVLSYLFL IFLQWMTPDS VIDVAIDATG PRRAWTHQWP RDKKRDENDK 480 VSKSR 485 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PIGA | 102187116 | A0A452F3Q4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PIGA | 5277 | P37287 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Piga | 18700 | Q64323 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PIGA | A0A2I3TBL1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PIGA | F1SQU5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | PIGA | 103351771 | A0A5F9CR14 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Piga | 363464 | D4AAY7 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | piga | 791759 | B0S6Z8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex |
| GO:0016021 | integral component of membrane |
| GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity |
| GO:1990830 | cellular response to leukemia inhibitory factor |
| GO:0006506 | GPI anchor biosynthetic process |