Gene: WDPCP

Basic information

Tag Content
Uniprot ID F1Q1T8
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCAFP00000004653
Ensembl nucleotide ID ENSCAFG00000003119
Gene name WD repeat containing planar cell polarity effector
Gene symbol WDPCP
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSFCLTELHL WSLKNTLHIG DRDIGIYQYY DKKDPPVSLT EHGNIEEKQK LAESRDYPWT 60
LKNRRPEKLR DSLKELEELM QNSHCVLSKW KNKYVCRLLF GSGVLVSLSL SGPQLEKVVI 120
DRSLVGKLIS DSISDALLTD SFIILSFLAQ NKLCFIQFTK KMGSPDTNKR LEKLSALDYK 180
ISYYEIPGPV NRTTERRLAI NCVQDIVVCW WPLVSDDAWP WAPISPEKDR ANLLLLGYAQ 240
GRLEVLSCIR TEWDPLDVRF GTKQPYQVLT VERSISVDKE PMADSCIYEY VRNKIQCISV 300
TRIPLKSKAI SCCRNVTEDK LILGCEDSSV ILYETHRRVT LLAHAELLPS LISCHPSGAI 360
LLVGSNQGEL QIFDMALSPI NIQLLAEDRS PRKTLQFNKF FDISSSLVQM QWIAPPLVSE 420
KPERGDIYDL LFLRFDRGPL GALLFKLGIF TQGQLGLTDI IFQYIHCDEI YEAINILSSM 480
NWDTLGHECF ISMSAIVNHL LRQKLTPERE AQLEASLGTF YAPTRPLLDT TILEYRDEIS 540
KYARRFFHHL LRYQRFEKAF LLAVDIGARD LFMDIHYFAL DKGELALAEV ARKRACDIDA 600
ESITSGVELL GPLDRGDMLN EAFVGLSLAP QGEDKFPDNL PPSCSVHKHI IQQRTLNDSS 660
NRQVLDGRNE LEKDTRAESL MTKTCNEEGE MREDCEEQEI GDGGSLRMVH FGLVQTPHPI 720

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologWDPCPF1Q1T8Canis lupus familiarisPredictionMore>>
1:1 orthologWDPCPA0A452F7N6Capra hircusPredictionMore>>
1:1 orthologWDPCP51057O95876Homo sapiensPredictionMore>>
1:1 orthologWdpcp216560Q8C456CPOMus musculusPublicationMore>>
1:1 orthologWDPCP459270H2R2S2Pan troglodytesPredictionMore>>
1:1 orthologA0A287AI40Sus scrofaPredictionMore>>
1:1 orthologWdpcpA0A0G2JXB0Rattus norvegicusPredictionMore>>
1:1 orthologwdpcp100333125E7F9Q9Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0097541 axonemal basal plate
GO:0002093 auditory receptor cell morphogenesis
GO:0043010 camera-type eye development
GO:0072358 cardiovascular system development
GO:0060271 cilium assembly
GO:0055123 digestive system development
GO:0042733 embryonic digit morphogenesis
GO:0045184 establishment of protein localization
GO:0090521 glomerular visceral epithelial cell migration
GO:0001822 kidney development
GO:2000114 regulation of establishment of cell polarity
GO:0010762 regulation of fibroblast migration
GO:0051893 regulation of focal adhesion assembly
GO:1900027 regulation of ruffle assembly
GO:0060541 respiratory system development
GO:0060021 roof of mouth development
GO:0007224 smoothened signaling pathway
GO:0043587 tongue morphogenesis

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR024511 Frtz
IPR036322 WD40_repeat_dom_sf

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF11768 Frtz