Gene: mmachc

Basic information

Tag Content
Uniprot ID F1QZ86
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000117903
Ensembl nucleotide ID ENSDARG00000043877
Gene name Alkylcobalamin:glutathione S-alkyltransferase
Gene symbol mmachc
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
XCSTSAPLHW GRKCTSSTPL RRRKMAISSE RVEELLRTFR ESLKAKGFEI YPFKVGWYNA 60
VLTAAHHLQY PADTLAVLVI STPAMFECAF LPFLQSQSCE SLRDPIDQCT AHTLSACISL 120
CFANQFVDVS YDYEMLPSRK PKFLAQTAAH VSGAAYYYQT SDIHNPPWGE KKMFGVCVHP 180
QLGGWFAIRA LLVFRDVQAG AGFQQRDPAD CVCTQEERIR LLESFNLRWR DWSYRDIVPA 240
EDRYSDQQKQ YFITPPGQRR ALLRQWGYLT DTQS 274

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologMMACHCQ5E9C8Bos taurusPredictionMore>>
1:1 orthologMMACHC102183931A0A452G8L9Capra hircusPredictionMore>>
1:1 orthologMMACHC25974Q9Y4U1Homo sapiensPredictionMore>>
1:1 orthologMmachc67096Q9CZD0CPOMus musculusPublicationMore>>
1:1 orthologMMACHC469180H2PYX3Pan troglodytesPredictionMore>>
1:1 orthologMMACHC100347413G1SQ06Oryctolagus cuniculusPredictionMore>>
1:1 orthologMmachc313520D4A729Rattus norvegicusPredictionMore>>
1:1 orthologmmachcF1QZ86Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0031419 cobalamin binding
GO:0033787 cyanocobalamin reductase (cyanide-eliminating) activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0846 Cobalamin
KW-0170 Cobalt
KW-0963 Cytoplasm
KW-0521 NADP
KW-0560 Oxidoreductase
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR032037 MMACHC

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF16690 MMACHC