Gene: TBC1D32

Basic information

Tag Content
Uniprot ID F1SF42
Entrez ID 100156680
Genbank protein ID HDB36648.1; HDA46509.1;
Genbank nucleotide ID XM_001926894.4
Ensembl protein ID ENSSSCP00000004581
Ensembl nucleotide ID ENSSSCG00000004242
Gene name Protein broad-minded isoform X1
Gene symbol TBC1D32
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAHFSGEDQA MLQAMLRQLF HSVKEKITGA PSLECAEEIL LHLEETDENF HNYEFVKYLR 60
QHICNTLGPM IEDEMEKWTS NQNQGDEFGY DTIVQHVTKR TQESREYKEM MHSLKNIMMI 120
VVESMINKFE EDEIRSQERR RKIQKEKSSS YCTDNCSDSD SSFNQSYKFC QGKLQLILDQ 180
LDPGQPKEVR YEALQTLCSA PPSDVLNCEN WTTLCEKLTV FLSDPDPVFS DRILKFYAQT 240
FTLSPLHMTK EIYTSLAKYL ELYFLSRESH IPTLSTGVDI TNSNVNRLLK KVRLLNEYQK 300
EAPSFWIRHP EKYMEEIVES TLSLLSLKHD QSHLVSQKIL DPIYFLALVD AKAVWFKKWM 360
HAYYSRTTVL RLLEKKYKSL ITTAVQQCVQ YFELCETMKA NEVLRHSKPC GNKQKTFYYS 420
GQELQYIYFI HSVCLLGRLL IYKQGRKLFP VKLKNRKDLV SLTDLLVLFT QLIYYSPSCP 480
KMMTSVHLEN YSPASMVTEV LRILCDQKEC AVECLCNNTV MEALLQPVHN LMKGTKAAPH 540
CSETALIHIA DILARIASVE EGLILLLYGE NMNSSEEKSP TGAHIIAQFL KKLLDEDISI 600
FSGSEMFPVV KGAFTSVCRQ IYGTCEGLQV LVPYSLHESI AKEWKKTSLL SERLPTPIEG 660
SDSVSSVSQG SQNIVAWEEN LLDDLLNFAA TPKGLLLLQR TGAINECVTF MFNRYAKKLQ 720
ISRHKKFGYG VLVTQVASTA AGAIALQSSG FINSLITELW ANLECGRDDV RVTHPRSTPV 780
DPIDRSCQKS FLALVNLLSY PAVYELIGNQ GLPNKAEYSL REVPACIIDI IDRLIILNSE 840
AKIRSLFNYE QSHIFGLRLL SVVCCNLDTL LLLEAQYQVS EMLLNAQEEN TLDTSESHRD 900
FIIDSLSVER NHVLVRINLI GGPVERLLPP RILEKGDDPY PWPMFSSYPL PKCYMSDCVT 960
RNADLKQDND LGKLFLRFKT SDKQTEWIEN CRRQFRKMMK AKPDIISGAA LGELLEKLVL 1020
HLSESPSECY FPPVEYTATD ANVKNESLSS VQQLGVKMTV RYGKFLKLLK DGAESDLTLV 1080
LKHCERFLKQ QQACVKSSLL CLQGSYTGHD WFVSSLFMIM LGDKEKTFRF LQQFSRLLTS 1140
AFLWLPRLHI SRYLPMDTIE SGIHPVYFCS THYIEMLLKA EVPLVFSAFH MSGFAPSQIC 1200
LQWITQCFWN YLDWIEICHY IATCVFLGPD YQVYICIAIF KHLQQDILQH TQTQDLQVFL 1260
KEEALQGFRV SAYFDYMEIL EQNYRPVLLR DMRNIRVQST

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTBC1D32F1PS18Canis lupus familiarisPredictionMore>>
1:1 orthologTBC1D32A0A452FLC7Capra hircusPredictionMore>>
1:1 orthologTBC1D32221322Q96NH3Homo sapiensPredictionMore>>
1:1 orthologTbc1d32544696Q3URV1CPOMus musculusPublicationMore>>
1:1 orthologTBC1D32472114A0A2I3TUU2Pan troglodytesPredictionMore>>
1:1 orthologTBC1D32100156680F1SF42Sus scrofaPredictionMore>>
1:1 orthologTbc1d32D4A050Rattus norvegicusPredictionMore>>
1:1 orthologtbc1d32566474Q5RHR6Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0060271 cilium assembly
GO:0007368 determination of left/right symmetry
GO:0042733 embryonic digit morphogenesis
GO:0007507 heart development
GO:0002088 lens development in camera-type eye
GO:1905515 non-motile cilium assembly
GO:0061512 protein localization to cilium
GO:0003406 retinal pigment epithelium development
GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR032735 BROMI
IPR035969 Rab-GTPase_TBC_sf
IPR039156 UPF0183/BROMI

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF14961 BROMI