Gene: ELAVL1

Basic information

Tag Content
Uniprot ID F6VTW3
Entrez ID
Genbank protein ID
Genbank nucleotide ID XM_001497883.5
Ensembl protein ID ENSECAP00000016914
Ensembl nucleotide ID ENSECAG00000019459
Gene name ELAV-like protein
Gene symbol ELAVL1
Organism Equus caballus
NCBI taxa ID 9796
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSNGYEDHMA EDCRDDIGRT NLIVNYLPQN MTQDELRSLF SSIGEVESAK LIRDKVAGHS 60
LGYGFVNYVT AKDAERAVNT LNGLRLQSKT IKVSYARPSS EVIKDANLYI SGLPRTMTQK 120
DVEDMFSRFG RIINSRVLVD QTTGLSRGVA FIRFDKRSEA EEAITSFNGH KPPGSSEPIT 180
VKFAANPNQN KNVALLSQLY HSPARRFGGP VHHQAQRFRF SPMGVDHMSG LSGVNVPGNA 240
SSGWCIFIYN LGQDADEGIL WQMFGPFGAV TNVKVIRDFN TNKCKGFGFV TMTNYEEAAM 300
AIASLNGYRL GDKILQVSFK TNKSHK 326

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologELAVL1617316Q3ZCE2Bos taurusPredictionMore>>
1:1 orthologELAVL1102173732A0A452EKQ9Capra hircusPredictionMore>>
1:1 orthologELAVL1F6VTW3Equus caballusPredictionMore>>
1:1 orthologELAVL11994Q15717Homo sapiensPredictionMore>>
1:1 orthologElavl115568P70372CPOMus musculusPublicationMore>>
1:1 orthologELAVL1743010K7D3Q8Pan troglodytesPredictionMore>>
1:1 orthologELAVL1100337681D3K5N7Sus scrofaPredictionMore>>
1:1 orthologElavl1363854B5DF91Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005829 cytosol
GO:0005654 nucleoplasm
GO:1990904 ribonucleoprotein complex
GO:0003725 double-stranded RNA binding
GO:0035198 miRNA binding
GO:0035925 mRNA 3'-UTR AU-rich region binding
GO:0042803 protein homodimerization activity
GO:0019901 protein kinase binding
GO:0070935 3'-UTR-mediated mRNA stabilization
GO:0060965 negative regulation of gene silencing by miRNA
GO:0045727 positive regulation of translation
GO:0051260 protein homooligomerization

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0677 Repeat
KW-0694 RNA-binding

Interpro

InterPro ID InterPro Term
IPR006548 ELAD_HU_SF
IPR034775 ELAV/Hu_RRM1
IPR002343 Hud_Sxl_RNA
IPR034996 HuR_RRM2
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom

PROSITE

PROSITE ID PROSITE Term
PS50102 RRM

Pfam

Pfam ID Pfam Term
PF00076 RRM_1