| Tag | Content |
|---|---|
| Uniprot ID | G3V989 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000039406 |
| Ensembl nucleotide ID | ENSRNOG00000034177 |
| Gene name | Ephrin-A5 |
| Gene symbol | Efna5 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | FLPLLFLVLD RSFMTADIGE HLFAQNYLFS PSVSNRFQRG DYHIDVCIND YLDVFCPHYE 60 DSVPEDKTER YVLYMVNFDG YSACDHTSKG FKRWECNRPH SPNGPLKFSE KFQLFTPFSL 120 GFEFRPGREY FYISSAIPDN GRRSCLKLKV FVRPTNSCMK TIGVHDRVFD VNDKVENSLE 180 PADDTVHESA EPSRGENAAQ TPRIPSRLLA ILLFLLAMLL TL 222 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EFNA5 | A0A452EE67 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | EFNA5 | 1946 | P52803 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Efna5 | 13640 | O08543 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | EFNA5 | 471594 | A0A2I3SW52 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | EFNA5 | A0A287AHP3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Efna5 | G3V989 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005912 | adherens junction |
| GO:0031362 | anchored component of external side of plasma membrane |
| GO:0005604 | basement membrane |
| GO:0098982 | GABA-ergic synapse |
| GO:0045499 | chemorepellent activity |
| GO:0046875 | ephrin receptor binding |
| GO:0005169 | neurotrophin TRKB receptor binding |
| GO:0071372 | cellular response to follicle-stimulating hormone stimulus |
| GO:1904322 | cellular response to forskolin |
| GO:0048668 | collateral sprouting |
| GO:0048013 | ephrin receptor signaling pathway |
| GO:1900025 | negative regulation of substrate adhesion-dependent cell spreading |
| GO:0048672 | positive regulation of collateral sprouting |
| GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation |
| GO:0051965 | positive regulation of synapse assembly |
| GO:0032956 | regulation of actin cytoskeleton organization |
| GO:0022407 | regulation of cell-cell adhesion |
| GO:0051893 | regulation of focal adhesion assembly |
| GO:0043087 | regulation of GTPase activity |
| GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus |
| GO:0070507 | regulation of microtubule cytoskeleton organization |
| GO:0031290 | retinal ganglion cell axon guidance |
| GO:0099560 | synaptic membrane adhesion |
| Pfam ID | Pfam Term |
|---|---|
| PF00812 | Ephrin |