| Tag | Content |
|---|---|
| Uniprot ID | H2R068 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000040250 |
| Ensembl nucleotide ID | ENSPTRG00000020339 |
| Gene name | Musculin |
| Gene symbol | MSC |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | VWQFLQLTAV RADSGLGRQL VVHAPRGQQR GAHALATHLA FSPRASRPGF LVFLGALSGL 60 RLRQGAEGGD SETGQGGGKR TRVGKGDNGM STGSVSDPEE MELRGLQREY PVPASKRPPL 120 RGVERSYASP SDNSSAEEED PDGEEERCAL GTAGSAEGCK RKRPRVAGGG GAGGSAGGGG 180 KKPLPAKGSA AECKQSQRNA ANARERARMR VLSKAFSRLK TSLPWVPPDT KLSKLDTLRL 240 ASSYIAHLRQ LLQEDRYENG YVHPVNLTWP FVVSGRPDSD TKEVSAANRL CGTTA 295 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MSC | 507407 | G3X7V5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MSC | 486992 | E2R7N0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | MSC | 108637528 | A0A452EHD7 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MSC | 9242 | O60682 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Msc | 17681 | O88940 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | MSC | H2R068 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | MSC | 100155518 | F1RWI0 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | MSC | 100338807 | G1SSJ5 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Msc | 312897 | D3ZWP1 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0046983 | protein dimerization activity |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0014707 | branchiomeric skeletal muscle development |
| GO:1990830 | cellular response to leukemia inhibitory factor |
| GO:0060539 | diaphragm development |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0060021 | roof of mouth development |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50888 | BHLH |
| Pfam ID | Pfam Term |
|---|---|
| PF00010 | HLH |