| Tag | Content |
|---|---|
| Uniprot ID | H2RBQ2; A0A2J8MEQ4; |
| Entrez ID | 472642 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001153018.4 |
| Ensembl protein ID | ENSPTRP00000056099 |
| Ensembl nucleotide ID | ENSPTRG00000018968 |
| Gene name | Sp8 transcription factor |
| Gene symbol | SP8 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MATSLLGEEP RLGSTPLAML AATCNKIGSP SPSPSSLSDS SSSFGKGFHP WKRSSSSSSA 60 SCNVVGSSLS SFGVSGASRN GSSSSAAAAA AAAAAAAAAL VSDSFSCGGS PGSSAFSLTS 120 SSAAAAAAAA AAAASSSPFA NDYSVFQAPG VSGGSGGGGG GGGGGSSAHS QDGSHQPVFI 180 SKVHTSVDGL QGIYPRVGMA HPYESWFKPS HPGLGAAGEV GSAGASSWWD VGAGWIDVQN 240 PNSAAALPGS LHPAAGGLQT SLHSPLGGYN SDYSGLSHSA FSSGASSHLL SPAGQHLMDG 300 FKPVLPGSYP DSAPSPLAGA GGSMLSAGPS APLGGSPRSS ARRYSGRATC DCPNCQEAER 360 LGPAGASLRR KGLHSCHIPG CGKVYGKTSH LKAHLRWHTG ERPFVCNWLF CGKRFTRSDE 420 LQRHLRTHTG EKRFACPVCN KRFMRSDHLS KHVKTHSGGG GGGSAGSGSG GKKGSDTDSE 480 HSAAGSPPCH SPELLQPPEP GHRNGLE 507 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SP8 | 102177029 | A0A452E4Z3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SP8 | 221833 | Q8IXZ3 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Sp8 | 320145 | Q8BMJ8 | CPO,CLO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | SP8 | 472642 | H2RBQ2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Sp8 | 299499 | D3ZQL2 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | sp8b | 324931 | Q6P0J3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0003676 | nucleic acid binding |
| GO:0009953 | dorsal/ventral pattern formation |
| GO:0030326 | embryonic limb morphogenesis |
| GO:0009954 | proximal/distal pattern formation |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF00096 | zf-C2H2 |