| Tag | Content |
|---|---|
| Uniprot ID | K7C1N7; A0A2J8JNB5; |
| Entrez ID | |
| Genbank protein ID | JAA29045.1; JAA20219.1; JAA38167.1; JAA10450.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000078689 |
| Ensembl nucleotide ID | ENSPTRG00000015793 |
| Gene name | Discs large MAGUK scaffold protein 1 |
| Gene symbol | DLG1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPVRKQDTQR ALHLLEEYRS KLSQTEDRQL RSSIERVINI FQSNLFQALI DIQEFYEVTL 60 LDNPKCIDRS KPSEPIQPVN TWEISSLPSS TVTSETLPSS LSPSVEKYRY QDEDTPPQEH 120 ISPQITNEVI GPELVHVSEK NLSEIENVHG FVSHSHISPI KANPPPVLVN TDSLETPTYV 180 NGTDADYEYE EITLERGNSG LGFSIAGGTD NPHIGDDSSI FITKIITGGA AAQDGRLRVN 240 DCILRVNEVD VRDVTHSKAV EALKEAGSIV RLYVKRRKPV SEKIMEIKLI KGPKGLGFSI 300 AGGVGNQHIP GDNSIYVTKI IEGGAAHKDG KLQIGDKLLA VNNVCLEEVT HEEAVTALKN 360 TSDFVYLKVA KPTSMYMNDG YAPPDITNSS SQPVDNHVSP SSFLGQTPAS PARYSPVSKA 420 VLGDDEITRE PRKVVLHRGS TGLGFNIVGG EDGEGIFISF ILAGGPADLS GELRKGDRII 480 SVNSVDLRAA SHEQAAAALK NAGQAVTIVA QYRPEEYSRF EAKIHDLREQ MMNSSISSGS 540 GSLRTSQKRS LYVRALFDYD KTKDSGLPSQ GLNFKFGDIL HVINASDDEW WQARQVTPDG 600 ESDEVGVIPS KRRVEKKERA RLKTVKFNSK TRDKGQSFND KRKKNLFSRK FPFYKNKDQS 660 EQETSDADQH VTSNASDSES SYRGQEEYVL SYEPVNQQEV NYTRPVIILG PMKDRINDDL 720 ISEFPDKFGS CVPHTTRPKR DYEVDGRDYH FVTSREQMEK DIQEHKFIEA GQYNNHLYGT 780 SVQSVREVAE KGKHCILDVS GNAIKRLQIA QLYPISIFIK PKSMENIMEM NKRLTEEQAR 840 KTFERAMKLE QEFTEHFTAI VQGDTLEDIY NQVKQIIEEQ SGSYIWVPAK ERL 893 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | DLG1 | A0A452E2Y8 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | DLG1 | 1739 | Q12959 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Dlg1 | 13383 | Q811D0 | CPO | E12.5, E15.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | DLG1 | K7C1N7 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Dlg1 | A0A0G2K1M2 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | dlg1 | 114446 | Q5PYH6 | Danio rerio | Prediction | More>> |
| InterPro ID | InterPro Term |
|---|---|
| IPR016313 | DLG1-like |
| IPR019590 | DLG1_PEST_dom |
| IPR008145 | GK/Ca_channel_bsu |
| IPR008144 | Guanylate_kin-like_dom |
| IPR020590 | Guanylate_kinase_CS |
| IPR015143 | L27_1 |
| IPR004172 | L27_dom |
| IPR036892 | L27_dom_sf |
| IPR027417 | P-loop_NTPase |
| IPR001478 | PDZ |
| IPR019583 | PDZ_assoc |
| IPR036034 | PDZ_sf |
| IPR036028 | SH3-like_dom_sf |
| IPR001452 | SH3_domain |