| Tag | Content |
|---|---|
| Uniprot ID | Q5XIA0 |
| Entrez ID | 315952 |
| Genbank protein ID | AAH83786.1 |
| Genbank nucleotide ID | NM_001014095.1 |
| Ensembl protein ID | ENSRNOP00000074346; ENSRNOP00000019902; |
| Ensembl nucleotide ID | ENSRNOG00000014746 |
| Gene name | Zinc finger protein DZIP1L |
| Gene symbol | Dzip1l |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane. |
| Sequence | MQYSVATADG LSGPPSGAYT LPTFKFQPRR ESIDWRRISA VDVDRVAREL DVATLQENIA 60 GVTFCNLDRE VCNHCRQPVD PVLLKVLRLA QLIIEYLLHC QDCLSASVAQ LEARLQASLG 120 QQQRGQQELG RQADELKGVR EESRRRRKMI STLQQLLLQT GAHSYHTCHL CDKTFMNATF 180 LRGHIQRRHA GMAEVGKQKQ EQQLGEVLEE LRAKLKWTQG ELEAQREAER QRQAQELEMI 240 RQREIEAKKK FDEWKEKERS KLYGEIDKLK QLFWDEFKTV ANQNSTLEEK LKVLQSYSMT 300 ESHLGSLRDE ESEERLKHAQ ELQALREKMD IQKTEWKRKM KALHEERAAE RRQLQEENER 360 LHVTLSQDQK KAAAQSQRHI NALRAQLQEQ ARLIESQEET IQTLSFRRME EVQEVPKAVV 420 TEEDSSEEEL EASLEEQQEQ RKVLAALRNN PAWLKQFRPI LEDTLEEKLE GMGIKRGTKG 480 ISAQTVRRLE PLLRTQREQT ARSFREFLSL REKLNQEVSS RAKKRWEGTA VVPQPDGQPP 540 VKSQRTTLAT REVRPKTRTL TVALPSKPAE PSTSTPRGHS SHGPGLTQVS TPIPRPRVHG 600 PSSTPVSPGP GLSTPPFSSE EEPEGDVVQR VSLQPPKVLP RSAPQPEDNW GWSDSETSEE 660 SAQSPGKGSD GLASSATLVQ SMVKNLEKQL ETPAKKPSGG VNMFLRPNTA LQRSSTPARK 720 TQLSEDESDL EISSLEDLSH DLGPKGKPTP LSHSKLPEKF DASPWSSGSR PRIPGW 776 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | DZIP1L | A0A452ERJ9 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | DZIP1L | 199221 | Q8IYY4 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Dzip1l | 72507 | Q499E4 | CPO,CLP | Mus musculus | Publication | More>> | |
| 1:1 ortholog | DZIP1L | A0A2I3RUU2 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | DZIP1L | A0A287B413 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | DZIP1L | 100352428 | G1SKV1 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Dzip1l | 315952 | Q5XIA0 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | dzip1l | X1WEH0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005930 | axoneme |
| GO:0005814 | centriole |
| GO:0036064 | ciliary basal body |
| GO:0046872 | metal ion binding |
| GO:0003676 | nucleic acid binding |
| GO:1905349 | ciliary transition zone assembly |
| GO:0060271 | cilium assembly |
| GO:0033504 | floor plate development |
| GO:0021532 | neural tube patterning |
| GO:0061512 | protein localization to cilium |
| GO:0033365 | protein localization to organelle |
| GO:0032880 | regulation of protein localization |
| GO:0007224 | smoothened signaling pathway |
| Pfam ID | Pfam Term |
|---|---|
| PF13815 | Dzip-like_N |