Gene: Cramp1

Basic information

Tag Content
Uniprot ID Q6PG95; E9QNA8; Q6ZPR3;
Entrez ID 57354
Genbank protein ID BAC98166.1
Genbank nucleotide ID NM_020608.3; XM_006524703.3; XM_006524702.3; XM_017317589.1;
Ensembl protein ID ENSMUSP00000156906; ENSMUSP00000073060;
Ensembl nucleotide ID ENSMUSG00000038002
Gene name Protein cramped-like
Gene symbol Cramp1
Organism Mus musculus
NCBI taxa ID 10090
Cleft type CPO
Developmental stage
Data sources Manually collected
Reference 27933520
Functional description
Sequence
MTVKLGDAGS GEEGLKKLGK RTADEESLDG EGPGGADAAD SSSTKRDGQT PRASGAPAPP 60
RGLPTPSPPQ GSPQDQHHFL RSSVRPQSKR PRKDAPCALG SGGASGSGPR GKGSDGGASS 120
SGNVSGATPA TPAGGSRSSS RNIGSSGPEK EEGKKVRRQW ESWSTEDKNT FFEGLYEHGK 180
DFEAIQNNIA LKYKKKGKPA SMVKNKEQVR HFYYRTWHKI TKYIDFDNVF SRGLKKSSQE 240
LYGLICYGEL RKKIGGCMDD KNATKLNELI QVGATTVRYK GRNLRIKAPM CRALKKLCDP 300
DGLSDEEDQK PVRLPLKVPV ELQPRNNHAW ARVQSLAQNP RLRMIVELHR KVSSLIEFLK 360
QKWALHEVRI RKTLEERQLQ GSSTVQTQEK VALHLFPGEN CTLTPLPGVA RVVHSKAFCT 420
VHWQEGGRCK QGTKDIHSLP PAQILGIQSG QGIARGQLKC QRSSAEGKGG GRLLPTADAS 480
QSSGESSPES APAEGAAPSL SSPDAPDRPH GLQDSGPHLE KTPVTALAVG RDSPIQESGA 540
LPCPCGQPPD LEDELSLLDP FPRYLKSCQD LIIPEQCRRA DTRSGREHPP LGSVASPETL 600
TPSSGAVADS APPGLDPQPG TDHQPDTRLQ SDICTKELAN ASSEESQEKG SPSEHLSSQG 660
QPATRPSKEV PASQLAQQLR EEGWSLQTSE SLTLAEVYLM MGKPTKLQLE YDWLAVLGPE 720
SQAPTAQGQT ALSRSSPSAL HQQRLLSCLL RLISTEVHPK MAFEANTAST ASVRPTQEEQ 780
STTPPGKVVT INSRSPRCSR NPSTLRSNKT FPSASAPCSP GLRNPPRPLL VAGPSSTGSS 840
DSDGGLFAVP TTLPPNSRHG KLFSPSKEAE LTFRQHLDSI SIQSDFFSPK PKKLRKRHLR 900
KPLVVQRTLL PRPSENQSHN VCSFSILSNS PIAGRGWFRP IQSSLTKAAL SRPIVPKVLP 960
SQATSHLPSA IDLAAQSAGI IPGSPLPILD TDGSSGISPL SSEQATTAIS GQGDTGPHQN 1020
RDPVTAVRGT NDPFISVTRP EQEPMTDGFQ GSPALTLPEL SKANLQNGLS IPLPSSESSS 1080
TRLSPPNVSA LLDISLPGPP EDVLSQGEPA TQISDSIIEI AISSGQYSEG VPLSPAKLNG 1140
SDSSKSLPSP SSSPQPNWIA SPTHDPQWYP SDSADSSLSS LFASFISPEK SRKMLPTTVG 1200
ANSGTSLLGP SLLDGNSRDS FVSRSLADVA EVVDSQLVCM MNENSIDYIS RFNDLAQELS 1260
ITEPGRREVL FDGGGGGNPV GDLSQ 1285

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein structural annotations

3D structure in PDB database

There is no related protein structure for this gene.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCRAMP1520515E1BN92Bos taurusPredictionMore>>
1:1 orthologCRAMP1F1P887Canis lupus familiarisPredictionMore>>
1:1 orthologCRAMP1A0A452DN69Capra hircusPredictionMore>>
1:1 orthologCRAMP157585Q96RY5Homo sapiensPredictionMore>>
1:1 orthologCramp157354Q6PG95CPOMus musculusPublicationMore>>
1:1 orthologCRAMP1453823A0A2J8J7V5Pan troglodytesPredictionMore>>
1:1 orthologCRAMP1G1SMY0Oryctolagus cuniculusPredictionMore>>
1:1 orthologCramp1D3ZNU3Rattus norvegicusPredictionMore>>

Other genetic variants/mutations

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Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO ID GO Term Evidence
GO:0003677 DNA bindingIEA
GO:0003682 chromatin bindingIBA

GO:Biological Process

GO ID GO Term Evidence
GO:0008150 biological_processND

GO:Cellular Component

GO ID GO Term Evidence
GO:0005634 nucleusIBA

Reactome Pathway

Reactome ID Reactome Term Evidence

Drugs and compounds information

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Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0539 Nucleus
KW-0597 Phosphoprotein
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR001005 SANT/Myb
IPR017884 SANT_dom

PROSITE

PROSITE ID PROSITE Term
PS51293 SANT

Pfam

Pfam ID Pfam Term