| Tag | Content |
|---|---|
| Uniprot ID | Q9DFH2 |
| Entrez ID | 60641 |
| Genbank protein ID | AAM13696.1; AAM13695.1; AAG09814.1; |
| Genbank nucleotide ID | NM_131643.1 |
| Ensembl protein ID | ENSDARP00000006945 |
| Ensembl nucleotide ID | ENSDARG00000003293 |
| Gene name | HMG box transcription factor Sox9a |
| Gene symbol | sox9a |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MNLLDPYLKM TDEQEKCLSD APSPSMSEDS AGSPCPSASG SDTENTRPAE NSLLAADGTL 60 GDFKKDEEDK FPVCIREAVS QVLKGYDWTL VPMPVRVNGS SKNKPHVKRP MNAFMVWAQA 120 ARRKLADQYP HLHNAELSKT LGKLWRLLNE VEKRPFVEEA ERLRVQHKKD HPDYKYQPRR 180 RKSVKNGQSE SEDGSEQTHI SPNAIFKALQ QADSPASSMG EVHSPSEHSG QSQGPPTPPT 240 TPKTDTQPGK ADLKREARPL QENTGRPLSI NFQDVDIGEL SSDVIETFDV NEFDQYLPPN 300 GHQNAPYAGG YAAWMTKPQN GSPQSSQLTP LNPAEPDQPR TTHIKTEQLS PSHYNEQQGS 360 PQHISYGSFN VQHLQHYSTS FPSITRAQYD YSDSHQGGAS SYYTHAGGQS SGLYSTFSYM 420 SSSQRPMYTP IADSTGVPSI PQSNHSPQHW DQQPVYTQLS RP 462 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SOX9 | 106503295 | A0A452FKA9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SOX9 | 6662 | P48436 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Sox9 | 20682 | Q04887 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | SOX9 | H2QDR6 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | SOX9 | 396840 | F1RV30 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Sox9 | 140586 | F1LYL9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | sox9a | 60641 | Q9DFH2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005634 | nucleus |
| GO:0003682 | chromatin binding |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0048708 | astrocyte differentiation |
| GO:0051216 | cartilage development |
| GO:0060536 | cartilage morphogenesis |
| GO:0002062 | chondrocyte differentiation |
| GO:0035118 | embryonic pectoral fin morphogenesis |
| GO:0007507 | heart development |
| GO:0048839 | inner ear development |
| GO:0002009 | morphogenesis of an epithelium |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0048709 | oligodendrocyte differentiation |
| GO:0043049 | otic placode formation |
| GO:0030916 | otic vesicle formation |
| GO:0033339 | pectoral fin development |
| GO:0032332 | positive regulation of chondrocyte differentiation |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50118 | HMG_BOX_2 |