Gene: foxe1

Basic information

Tag Content
Uniprot ID R4GEW1
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000127024
Ensembl nucleotide ID ENSDARG00000079266
Gene name Forkhead box E1
Gene symbol foxe1
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
XQSDYSDFQA VLPLGAILTR VMPVVKVESD SPSETTLPVN DSQRAEPQRG RRRKRPLQRG 60
KPPYSYIALI SMAIANSPDR KLTLGGIYKF ITERFPFYRD NSKKWQNSIR HNLTLNDCFI 120
KIPREPGRPG KGNYWALDPN AEDMFESGSF LRRRKRFKRS DFTTYSSYVH ESPVFSPVQI 180
ARSAYANSVY SNMAVSPPYA QQLPSAYYQS SSPNFTAGQS RVFRINSLIG SPSRMGQNAE 240
MIPQQSCRSF SPESGSCSLG GPGFQHQSCN GETVLSCYSS SSNNMAFAYS GPGHGQTQVS 300
YPQASTQHYG PAGRMAISSL SPIAGDAVGD PYGRTSPAQL GSFVQYNNSG AVGSSGAYIR 360
HPAYSGNMDR FVSAT 375

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologFOXE1616734F1ME54Bos taurusPredictionMore>>
1:1 orthologFOXE1106502413A0A452DS04Capra hircusPredictionMore>>
1:1 orthologFOXE12304O00358CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologFoxe1110805Q8R2I0CPOMus musculusPublicationMore>>
1:1 orthologFOXE1100610790H2R467Pan troglodytesPredictionMore>>
1:1 orthologFOXE1100157892F1SSG9Sus scrofaPredictionMore>>
1:1 orthologFoxe1192274O08771Rattus norvegicusPredictionMore>>
1:1 orthologfoxe1R4GEW1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0009653 anatomical structure morphogenesis
GO:0030154 cell differentiation
GO:0048703 embryonic viscerocranium morphogenesis
GO:0003419 growth plate cartilage chondrocyte proliferation
GO:0006357 regulation of transcription by RNA polymerase II

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR001766 Fork_head_dom
IPR018122 TF_fork_head_CS_1
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf

PROSITE

PROSITE ID PROSITE Term
PS00657 FORK_HEAD_1
PS00658 FORK_HEAD_2
PS50039 FORK_HEAD_3

Pfam

Pfam ID Pfam Term
PF00250 Forkhead