| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 10425 |
Name | ARIH2 |
Synonym | ARI2|TRIAD1;ariadne homolog 2 (Drosophila);ARIH2;ariadne homolog 2 (Drosophila) |
Definition | ARI-2|E3 ubiquitin-protein ligase ARIH2|all-trans retinoic acid inducible RING finger|protein ariadne-2 homolog |
Position | 3p21 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | "We observed linkage evidence in four regions: 3q22 ([median log of the odds (LOD) = 3.43]), 3p12 (median LOD) = 2.35), 2p22 (median LOD = 2.21), and 13q21 (median LOD = 2.09). When used in conjunction with the non-parametric bootstrap, our approach yields high-resolution to identify candidate gene regions containing putative BMPR2-interacting genes. Imputation of the disease model by LOD-score maximization indicates that the 3q22 locus alone predicts most FPAH cases in BMPR2 mutation carriers, providing strong evidence that BMPR2 and the 3q22 locus interact epistatically." |
| More detail of all Human literatures about ARIH2 | |
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External Links |
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Links to Entrez Gene | 10425 |
Links to all GeneRIF Items | 10425 |
Links to iHOP | 10425 |
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Sequence Information |
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Nucleotide Sequence |
>10425 : length: 1482 atgtcagtggacatgaatagccaggggtctgacagcaatgaagaggactatgacccaaat tgtgaggaagaggaagaagaagaagaagacgaccctggggacatagaggactattacgtg ggagtagccagcgatgtggagcagcagggggctgatgcctttgatcccgaggagtaccag ttcacttgcttgacctacaaggaatctgagggtgccctcaatgagcacatgaccagctta gcttctgtcctaaaggtatctcattcagttgctaaacttatattagttaatttccactgg caagtttcagagatattggacagatacaagtccaattctgctcaactgcttgttgaggct cgagttcagcctaatccatcaaaacatgttcccacatcccatccccctcaccactgtgca gtgtgtatgcagtttgtgcgaaaggaaaacctactctctctggcctgtcagcaccagttt tgccgcagctgctgggagcagcactgctcagttctcgtcaaggacggcgtgggcgtggga gtctcttgcatggctcaggactgtccactccgtacaccagaggactttgtgtttccattg cttcccaatgaagaattgagagagaaatacaggcgctacctcttcagggactatgtggag agtcattaccagctccagctgtgccctggtgcagactgccccatggttattcgggtacag gagcctagagctcgccgagtacagtgcaatcggtgcaacgaggtcttctgtttcaagtgt cgtcagatgtatcacgcacccacagactgtgccacaatccggaaatggctcacgaagtgt gcagacgactctgaaacagccaactacattagtgctcacactaaagactgtcccaagtgc aacatctgcattgagaagaatggaggctgcaatcacatgcaatgctccaaatgtaaacac gacttctgctggatgtgtctaggagattggaagactcatggcagtgaatactatgagtgc agtcgttacaaggagaatcctgacatcgtgaaccagagccaacaagcccaggcgagggaa gccctcaagaagtacttattctactttgagaggtgggaaaaccacaataaaagcttgcag ctagaggcacagacataccagcggattcacgagaagattcaggagagggtcatgaacaat ctggggacatggatcgactggcagtacctacagaatgctgccaagctcttggccaagtgt cgatacaccctgcaatacacctacccatatgcatattacatggagtccggacccaggaag aagctgtttgaataccagcaggctcagctggaggctgagatcgaaaacctctcatggaaa gtggagcgtgcagacagctatgacagaggggacttggagaaccagatgcatatagcggag cagcggaggagaaccctgctgaaagatttccatgacacctaa |
Protein Sequence |
>10425 : length: 493 MSVDMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDVEQQGADAFDPEEYQ FTCLTYKESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEA RVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVG VSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQ EPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKC NICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQARE ALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKC RYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVERADSYDRGDLENQMHIAE QRRRTLLKDFHDT |