Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

10425

Name

ARIH2

Synonymous

ARI2|TRIAD1;ariadne homolog 2 (Drosophila);ARIH2;ariadne homolog 2 (Drosophila)

Definition

ARI-2|E3 ubiquitin-protein ligase ARIH2|all-trans retinoic acid inducible RING finger|protein ariadne-2 homolog

Position

3p21

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

Link to UCSC genome

Matched SNP location

dbSNP ID

Regulatory information

chr3:48956254-49023815chr3:48957147-48957147rs9850134Single_Nucleotides|eQTL|WDR6, Motifs|PWM|Oct-1, Chromatin_Structure|DNase-seq|Lncap, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|DNase-seq|Huh75, Chromatin_Structure|DNase-seq|A549, Chromatin_Structure|DNase-seq|Cll, Chromatin_Structure|DNase-seq|Stellate, Chromatin_Structure|DNase-seq|Huh7, Chromatin_Structure|DNase-seq|Panislets, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|FAIRE|Gm19239, Chromatin_Structure|DNase-seq|Hasp, Chromatin_Structure|DNase-seq|Gm19239, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|MAX
chr3:48956254-49023815chr3:48972892-48972892rs1134591Single_Nucleotides|eQTL|WDR6, Single_Nucleotides|eQTL|AMT, Single_Nucleotides|eQTL|NCKIPSD, Single_Nucleotides|eQTL|NICN1, Single_Nucleotides|eQTL|WDR6, Chromatin_Structure|DNase-seq|Hmvecdneo, Protein_Binding|ChIP-seq|GATA1, Protein_Binding|ChIP-seq|GATA1
chr3:48956254-49023815chr3:49000626-49000626rs4974083Single_Nucleotides|eQTL|APEH, Single_Nucleotides|eQTL|PLXNB1, Chromatin_Structure|DNase-seq|H7es

Transcription Factors   [Top]

Regulation From TransFac database

UbcH7(h) + Ari-2(h) <==> UbcH7(h):Ari-2(h) (binding)
Bub1(h) + Ari-2(h) <==> Bub1(h):Ari-2(h) (binding)
UTP-glucose-1-phosphate uridylyltransferase 2(h) + Ari-2(h) <==> UTP-glucose-1-phosphate uridylyltransferase 2(h):Ari-2(h) (binding)
Ari-2(h) + EEF1A(h) <==> Ari-2(h):EEF1A(h) (binding)
Ari-2(h) + EF1G(h) <==> Ari-2(h):EF1G(h) (binding)
Ari-2(h) + PTN(h) <==> Ari-2(h):PTN(h) (binding)
Ari-2(h) + L8(h) <==> Ari-2(h):L8(h) (binding)
Ari-2(h) + p53(h) <==> Ari-2(h):p53(h) (binding)
Ari-2(h) + dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial(h) <==> Ari-2(h):dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial(h) (binding)
Ari-2(h) + Scamp2(h) <==> Ari-2(h):Scamp2(h) (binding)
Ari-2(h) + Tip60(h) <==> Ari-2(h):Tip60(h) (binding)
Ari-2(h) + utp14A(h) <==> Ari-2(h):utp14A(h) (binding)
Ari-2(h) + Cnt-d2(h) <==> Ari-2(h):Cnt-d2(h) (binding)
ARIH2(h) --> Ari-2(h) (expression).
ARIH2(h) --> Ari-2(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for ARIH2

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 48929785 - 48931785Agilent_014791

chr3

Promoter: 48929785 - 48931785GSE27584

chr3

Promoter: 48929785 - 48931785Agilent_014791_44K


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