| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 1073 |
Name | CFL2 |
Synonym | NEM7;cofilin 2 (muscle);CFL2;cofilin 2 (muscle) |
Definition | cofilin, muscle isoform|cofilin-2|nemaline myopathy type 7 |
Position | 14q12 |
Gene Type | protein-coding |
|
PAH Type |
Description |
PAH | "Further analysis revealed that the interaction between LIMK1 and BMPR-II inhibited LIMK1's ability to phosphorylate cofilin, which could then be alleviated by addition of BMP4." |
| More detail of all Human literatures about CFL2 | |
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Pathways and Diseases |
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Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | Fc gamma R-mediated phagocytosis;KEGG PATHWAY;hsa04666 |
Pathway | Cytoskeletal regulation by Rho GTPase;PANTHER;P00016 |
Pathway | Caspase cascade in apoptosis;PID Curated;200148 |
Disease | Nemaline myopathy 7;OMIM |
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External Links |
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Links to Entrez Gene | 1073 |
Links to all GeneRIF Items | 1073 |
Links to iHOP | 1073 |
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Sequence Information |
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Nucleotide Sequence |
>1073 : length: 501 atggcttctggagttacagtgaatgatgaagtcatcaaagtttttaatgatatgaaagta aggaaatcttctacacaagaggagatcaaaaagagaaagaaagcagttctcttctgttta agcgatgacaaaagacaaataattgtagaggaagcaaagcagatcttggtgggtgacatt ggtgatactgtagaggacccctacacatcttttgtgaagttgctacctctgaatgattgc cgatatgctttgtacgatgccacatacgaaacaaaagagtctaagaaagaagacctagta tttatattctgggctcctgaaagtgcacctttaaaaagcaagatgatttatgctagctct aaagatgccattaaaaagaaatttacaggtattaaacatgagtggcaagtaaatggcttg gatgatattaaggaccgttcgacacttggagagaaattgggaggcaatgtagtagtttca cttgaaggaaaaccattataa |
Protein Sequence |
>1073 : length: 166 MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDI GDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASS KDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL |