| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1073 |
Name | CFL2 |
Synonymous | NEM7;cofilin 2 (muscle);CFL2;cofilin 2 (muscle) |
Definition | cofilin, muscle isoform|cofilin-2|nemaline myopathy type 7 |
Position | 14q12 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for CFL2 | |||
Transcription Factors [Top] |
|
Regulation From TransFac database |
beta-actin(h) + cofilin-2(h) <==> beta-actin(h):cofilin-2(h) (binding) | gamma-actin(h) + cofilin-2(h) <==> gamma-actin(h):cofilin-2(h) (binding) | CFL2(h) --> cofilin-2(h) (expression). | cofilin-2(h) + ATP --LIMK1-isoform1(h)--> cofilin-2(h){p} + ADP (phosphorylation) | CFL2(h) --> cofilin-2(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
3 | Phosphoserine. | Swiss-Prot 53.0 | 24 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 89 | Phosphotyrosine. | Swiss-Prot 53.0 | 3 | Phosphoserine (LIMK1) | 9655398;17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr14 |
Promoter: 34252285 - 34254285 | Agilent_014791 |
chr14 |
Promoter: 34253149 - 34255149 | Agilent_014791 |
chr14 |
Promoter: 34252285 - 34254285 | GSE27584 |
chr14 |
Promoter: 34253149 - 34255149 | GSE27584 |
chr14 |
Promoter: 34252285 - 34254285 | Agilent_014791_44K |