| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 135 |
Name | ADORA2A |
Synonym | ADORA2|RDC8|hA2aR;adenosine A2a receptor;ADORA2A;adenosine A2a receptor |
Definition | adenosine A2 receptor|adenosine receptor A2a|adenosine receptor subtype A2a |
Position | 22q11.23 |
Gene Type | protein-coding |
|
PAH Type |
Description |
PAH | Absence of the adenosine A2A receptor confers pulmonary arterial hypertension and increased pulmonary vascular remodeling in mice. |
| More detail of all Mouse literatures about ADORA2A | |
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Pathways and Diseases |
|
Pathway | Vascular smooth muscle contraction;KEGG PATHWAY;hsa04270 |
Pathway | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway;PANTHER;P00027 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Neuroactive ligand-receptor interaction;KEGG PATHWAY;hsa04080 |
Pathway | HIF-2-alpha transcription factor network;PID Curated;200030 |
Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway;PANTHER;P00026 |
Pathway | Calcium signaling pathway;KEGG PATHWAY;hsa04020 |
Pathway | NGF-independant TRKA activation;PID Reactome;500624 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Disease | caffeine consumption;GAD |
Disease | anxiety disorder;GAD |
Disease | Hypertension;FunDO |
Disease | Heart failure;FunDO |
Disease | Phobic anxiety disorder;FunDO |
Disease | Panic disorder;FunDO |
Disease | CHEMDEPENDENCY;GAD |
Disease | Cystic fibrosis;FunDO |
Disease | Huntington disease;FunDO |
Disease | panic disorder;GAD |
Disease | Asthma;FunDO |
Disease | caffeine-induced anxiety.;GAD |
Disease | NEUROLOGICAL;GAD |
Disease | Kidney failure;FunDO |
Disease | Schizophrenia;FunDO |
Disease | PSYCH;GAD |
Disease | Depression;FunDO |
Disease | Chronic obstructive airway disease;FunDO |
Disease | migraine migraine with aura;GAD |
Disease | Thrombocytosis;FunDO |
|
External Links |
|
Links to Entrez Gene | 135 |
Links to all GeneRIF Items | 135 |
Links to iHOP | 135 |
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Sequence Information |
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Nucleotide Sequence |
>135 : length: 1239 atgcccatcatgggctcctcggtgtacatcacggtggagctggccattgctgtgctggcc atcctgggcaatgtgctggtgtgctgggccgtgtggctcaacagcaacctgcagaacgtc accaactactttgtggtgtcactggcggcggccgacatcgcagtgggtgtgctcgccatc ccctttgccatcaccatcagcaccgggttctgcgctgcctgccacggctgcctcttcatt gcctgcttcgtcctggtcctcacgcagagctccatcttcagtctcctggccatcgccatt gaccgctacattgccatccgcatcccgctccggtacaatggcttggtgaccggcacgagg gctaagggcatcattgccatctgctgggtgctgtcgtttgccatcggcctgactcccatg ctaggttggaacaactgcggtcagccaaaggagggcaagaaccactcccagggctgcggg gagggccaagtggcctgtctctttgaggatgtggtccccatgaactacatggtgtacttc aacttctttgcctgtgtgctggtgcccctgctgctcatgctgggtgtctatttgcggatc ttcctggcggcgcgacgacagctgaagcagatggagagccagcctctgccgggggagcgg gcacggtccacactgcagaaggaggtccatgctgccaagtcactggccatcattgtgggg ctctttgccctctgctggctgcccctacacatcatcaactgcttcactttcttctgcccc gactgcagccacgcccctctctggctcatgtacctggccatcgtcctctcccacaccaat tcggttgtgaatcccttcatctacgcctaccgtatccgcgagttccgccagaccttccgc aagatcattcgcagccacgtcctgaggcagcaagaacctttcaaggcagctggcaccagt gcccgggtcttggcagctcatggcagtgacggagagcaggtcagcctccgtctcaacggc cacccgccaggagtgtgggccaacggcagtgctccccaccctgagcggaggcccaatggc tatgccctggggctggtgagtggagggagtgcccaagagtcccaggggaacacgggcctc ccagacgtggagctccttagccatgagctcaagggagtgtgcccagagccccctggccta gatgaccccctggcccaggatggagcaggagtgtcctga |
Protein Sequence |
>135 : length: 412 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS |