Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

135

Name

ADORA2A

Synonymous

ADORA2|RDC8|hA2aR;adenosine A2a receptor;ADORA2A;adenosine A2a receptor

Definition

adenosine A2 receptor|adenosine receptor A2a|adenosine receptor subtype A2a

Position

22q11.23

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

Link to UCSC genome

Matched SNP location

dbSNP ID

Regulatory information

chr22:24813847-24838328chr22:24830084-24830084rs5751873Single_Nucleotides|eQTL|ADORA2A, Chromatin_Structure|DNase-seq|Chorion, Chromatin_Structure|DNase-seq|Hepatocytes, Chromatin_Structure|DNase-seq|Hsmm, Chromatin_Structure|DNase-seq|Gm12892, Chromatin_Structure|DNase-seq|Gm19238, Chromatin_Structure|DNase-seq|Myometr, Chromatin_Structure|DNase-seq|Gm12891, Chromatin_Structure|DNase-seq|Ips, Chromatin_Structure|DNase-seq|Gliobla, Chromatin_Structure|DNase-seq|Gm19239, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|DNase-seq|Osteobl, Chromatin_Structure|DNase-seq|Hsmmt, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|DNase-seq|Huvec, Chromatin_Structure|DNase-seq|Gm19240, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|DNase-seq|Progfib, Chromatin_Structure|DNase-seq|Gm18507, Chromatin_Structure|FAIRE|Gm19239, Chromatin_Structure|FAIRE|Gm12878, Chromatin_Structure|DNase-seq|Cll, Chromatin_Structure|DNase-seq|Medullo, Chromatin_Structure|DNase-seq|Stellate, Chromatin_Structure|FAIRE|Gm18507, Chromatin_Structure|DNase-seq|Fibrop, Chromatin_Structure|DNase-seq|Panisd, Chromatin_Structure|DNase-seq|UrotsaUt189, Chromatin_Structure|DNase-seq|Urotsa, Chromatin_Structure|DNase-seq|8988t, Chromatin_Structure|DNase-seq|Aosmc, Chromatin_Structure|DNase-seq|Lncap, Chromatin_Structure|FAIRE|Huvec, Chromatin_Structure|DNase-seq|Hmec, Chromatin_Structure|DNase-seq|Panislets, Protein_Binding|ChIP-seq|ETS1, Protein_Binding|ChIP-seq|USF1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|TCF12, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|NFKB1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A
chr22:24813847-24838328chr22:24836222-24836222rs2236625Single_Nucleotides|eQTL|ADORA2A, Motifs|Footprinting|MZF1_5-13, Motifs|Footprinting|MZF1, Motifs|PWM|MZF1, Motifs|PWM|MZF1_5-13, Motifs|PWM|Egr1, Motifs|PWM|Gabpa, Chromatin_Structure|DNase-seq|Chorion, Chromatin_Structure|FAIRE|Huvec, Chromatin_Structure|DNase-seq|Medullo, Chromatin_Structure|DNase-seq|Huvec

Transcription Factors   [Top]

Regulation From TransFac database

ADORA2A(h) --> A2A(h) (expression).
ADORA2A(h) --> A2A(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

154N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr22

Promoter: 23157592 - 23159592Agilent_014791

chr22

Promoter: 23157592 - 23159592GSE27584


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