| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 1889 |
Name | ECE1 |
Synonym | ECE;endothelin converting enzyme 1;ECE1;endothelin converting enzyme 1 |
Definition | ECE-1|endothelin-converting enzyme 1 |
Position | 1p36.1 |
Gene Type | protein-coding |
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PAH Type |
Description |
PH | Effect of small hairpin RNA targeting endothelin-converting enzyme-1 in monocrotaline-induced pulmonary hypertensive rats. |
| More detail of all Rat literatures about ECE1 | |
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Pathways and Diseases |
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Pathway | Endothelin signaling pathway;PANTHER;P00019 |
Disease | Hypertension;FunDO |
Disease | Diabetes mellitus;FunDO |
Disease | atherosclerosis, coronary;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Hypertension, essential, susceptibility to;OMIM |
Disease | ventricular arrhythmia, malignant;GAD |
Disease | Hirschsprung disease, cardiac defects, and autonomic dysfunction;OMIM |
Disease | Atherosclerosis;FunDO |
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External Links |
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Links to Entrez Gene | 1889 |
Links to all GeneRIF Items | 1889 |
Links to iHOP | 1889 |
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Sequence Information |
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Nucleotide Sequence |
>1889 : length: 2277 atgcctctccagggcctgggcctgcagcggaaccccttcctccaagggaagcggggcccg gggctcacgtcttccccgcccctcctgcctccttccctgcaggtgaacttccacagcccc cggagtggccagaggtgctgggctgcacggacccaggtggagaagcggctggtggtgttg gtggtacttctggcggcaggactggtggcctgcttggcagcactgggcatccagtaccag acaagatccccctctgtgtgcctgagcgaagcttgtgtctcagtgaccagctccatcttg agctccatggaccccacagtggacccctgccatgacttcttcagctacgcctgtgggggc tggatcaaggccaacccagtccctgatggccactcacgctgggggaccttcagcaacctc tgggaacacaaccaagcaatcatcaagcacctcctcgaaaactccacggccagcgtgagc gaggcagagagaaaggcgcaagtatactaccgtgcgtgcatgaacgagaccaggatcgag gagctcagggccaaacctctaatggagttgattgagaggctcgggggctggaacatcaca ggtccctgggccaaggacaacttccaggacaccctgcaggtggtcaccgcccactaccgc acctcacccttcttctctgtctatgtcagtgccgattccaagaactccaacagcaacgtg atccaggtggaccagtctggcctgggcttgccctcgagagactattacctgaacaaaact gaaaacgagaaggtgctgaccggatatctgaactacatggtccagctggggaagctgctg ggcggcggggacgaggaggccatccggccccagatgcagcagatcttggactttgagacg gcactggccaacatcaccatcccacaggagaagcgccgtgatgaggagctcatctaccac aaagtgacggcagccgagctgcagaccttggcacccgccatcaactggttgccttttctc aacaccatcttctaccccgtggagatcaatgaatccgagcctattgtggtctatgacaag gaataccttgagcagatctccactctcatcaacaccaccgacagatgcctgctcaacaac tacatgatctggaacctggtgcggaaaacaagctccttccttgaccagcgctttcaggac gccgatgagaagttcatggaagtcatgtacgggaccaagaagacctgtcttcctcgctgg aagttttgcgtgagtgacacagaaaacaacctgggctttgcgttgggccccatgtttgtc aaagcaaccttcgccgaggacagcaagagcatagccaccgagatcatcctggagattaag aaggcatttgaggaaagcctgagcaccctgaagtggatggatgaggaaacccgaaaatca gccaaggaaaaggccgatgccatctacaacatgataggataccccaacttcatcatggat cccaaggagctggacaaagtgtttaatgactacactgcagttccagacctctactttgaa aatgccatgcggtttttcaacttctcatggagggtcactgccgatcagctcaggaaagcc cccaacagagatcagtggagcatgaccccgcccatggtgaacgcctactactcgcccacc aagaatgagattgtgtttccggccgggatcctgcaggcaccattctacacacgctcctca cccaaggccttaaactttggtggcataggtgtcgtcgtgggccatgagctgactcatgct tttgatgatcaaggacgggagtatgacaaggacgggaacctccggccatggtggaagaac tcatccgtggaggccttcaagcgtcagaccgagtgcatggtagagcagtacagcaactac agcgtgaacggggagccggtgaacgggcggcacaccctgggggagaacatcgccgacaac gggggtctcaaggcggcctatcgggcttaccagaactgggtgaagaagaacggggctgag cactcgctccccaccctgggcctcaccaataaccagctcttcttcctgggctttgcacag gtctggtgctccgtccgcacacctgagagctcccacgaaggcctcatcaccgatccccac agcccctctcgcttccgggtcatcggctccctctccaattccaaggagttctcagaacac ttccgctgcccacctggctcacccatgaacccgcctcacaagtgcgaagtctggtaa |
Protein Sequence |
>1889 : length: 758 MPLQGLGLQRNPFLQGKRGPGLTSSPPLLPPSLQVNFHSPRSGQRCWAARTQVEKRLVVL VVLLAAGLVACLAALGIQYQTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGG WIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTASVSEAERKAQVYYRACMNETRIE ELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNV IQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFET ALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDK EYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRW KFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKS AKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKA PNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHA FDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADN GGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPH SPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW |