| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1889 |
Name | ECE1 |
Synonymous | ECE;endothelin converting enzyme 1;ECE1;endothelin converting enzyme 1 |
Definition | ECE-1|endothelin-converting enzyme 1 |
Position | 1p36.1 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
|
Link to UCSC genome |
Matched SNP location |
dbSNP ID |
Regulatory information |
chr1:21543740-21671997 | chr1:21664475-21664475 | rs3026815 | Single_Nucleotides|eQTL|USP48, Chromatin_Structure|FAIRE|Huvec, Chromatin_Structure|DNase-seq|Gm06990, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Huvec, Chromatin_Structure|DNase-seq|Helas3, Chromatin_Structure|DNase-seq|Jurkat, Chromatin_Structure|DNase-seq|Stellate, Chromatin_Structure|DNase-seq|Hre, Chromatin_Structure|DNase-seq|Myometr, Chromatin_Structure|DNase-seq|Huh7, Chromatin_Structure|DNase-seq|Aosmc, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Ag04450, Chromatin_Structure|DNase-seq|Cmk, Chromatin_Structure|DNase-seq|Hepg2, Chromatin_Structure|DNase-seq|Fibrop, Chromatin_Structure|DNase-seq|Hmvecdblad, Chromatin_Structure|DNase-seq|Hmvecdblneo, Chromatin_Structure|DNase-seq|Panc1, Chromatin_Structure|DNase-seq|Hmvecdlyneo, Chromatin_Structure|DNase-seq|Hmvecdneo, Protein_Binding|ChIP-seq|REST, Protein_Binding|ChIP-seq|ZNF263 |
|---|---|---|---|
Transcription Factors [Top] |
|
Regulation From TransFac database |
ECE1(h) --> ECE-1a(h) (expression). | NT(h) --ECE-1a(h)--> protein remnants (processing) | angiotensin I(v.s.) --ECE-1a(h)--> protein remnants (processing) | bradykinin(v.s.) --ECE-1a(h)--> protein remnants (processing) | Substance P(v.s.) --ECE-1a(h)--> protein remnants (processing) | ECE1(h) --> ECE-1(h) (expression). |
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Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
34 | Phosphoserine. | Swiss-Prot 53.0 | 166 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 187 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 210 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 270 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 316 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 362 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 383 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 539 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 632 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 651 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 34 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr1 |
Promoter: 21488994 - 21490994 | Agilent_014791 |
chr1 |
Promoter: 21488994 - 21490994 | GSE27584 |
chr1 |
Promoter: 21488994 - 21490994 | Agilent_014791_44K |