| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 2353 |
Name | FOS |
Synonym | AP-1|C-FOS|p55;FBJ murine osteosarcoma viral oncogene homolog;FOS;FBJ murine osteosarcoma viral oncogene homolog |
Definition | FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS)|G0/G1 switch regulatory protein 7|activator protein 1|cellular oncogene c-fos|proto-oncogene c-Fos |
Position | 14q24.3 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | "Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH." |
PH | "Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH." |
| More detail of all Human literatures about FOS | |
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Pathways and Diseases |
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Pathway | pertussis toxin-insensitive ccr5 signaling in macrophage;PID BioCarta;100214 |
Pathway | il-2 receptor beta chain in t cell activation;PID BioCarta;100129 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | LPA receptor mediated events;PID Curated;200011 |
Pathway | Ras signaling in the CD4+ TCR pathway;PID Curated;200088 |
Pathway | B cell receptor signaling pathway;KEGG PATHWAY;hsa04662 |
Pathway | ErbB2/ErbB3 signaling events;PID Curated;200119 |
Pathway | igf-1 signaling pathway;PID BioCarta;100136 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | HIF-1-alpha transcription factor network;PID Curated;200172 |
Pathway | IL12 signaling mediated by STAT4;PID Curated;200197 |
Pathway | oxidative stress induced gene expression via nrf2;PID BioCarta;100238 |
Pathway | Regulation of nuclear SMAD2/3 signaling;PID Curated;200002 |
Pathway | pdgf signaling pathway;PID BioCarta;100077 |
Pathway | ATF-2 transcription factor network;PID Curated;200116 |
Pathway | IL12-mediated signaling events;PID Curated;200034 |
Pathway | Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade;PANTHER;P00032 |
Pathway | PDGFR-alpha signaling pathway;PID Curated;200140 |
Pathway | FOXM1 transcription factor network;PID Curated;200120 |
Pathway | Glucocorticoid receptor regulatory network;PID Curated;200077 |
Pathway | BCR signaling pathway;PID Curated;200005 |
Pathway | calcium signaling by hbx of hepatitis b virus;PID BioCarta;100150 |
Pathway | Calcium signaling in the CD4+ TCR pathway;PID Curated;200159 |
Pathway | il 3 signaling pathway;PID BioCarta;100128 |
Pathway | Regulation of Telomerase;PID Curated;200072 |
Pathway | mapkinase signaling pathway;PID BioCarta;100113 |
Pathway | T cell receptor signaling pathway;KEGG PATHWAY;hsa04660 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | Osteopontin-mediated events;PID Curated;200042 |
Pathway | T cell activation;PANTHER;P00053 |
Pathway | Nongenotropic Androgen signaling;PID Curated;200145 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | IL2-mediated signaling events;PID Curated;200082 |
Pathway | Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039 |
Pathway | Colorectal cancer;KEGG PATHWAY;hsa05210 |
Pathway | inhibition of cellular proliferation by gleevec;PID BioCarta;100154 |
Pathway | Activation of the AP-1 family of transcription factors;PID Reactome;500458 |
Pathway | fc epsilon receptor i signaling in mast cells;PID BioCarta;100165 |
Pathway | tsp-1 induced apoptosis in microvascular endothelial cell;PID BioCarta;100010 |
Pathway | signal transduction through il1r;PID BioCarta;100132 |
Pathway | mets affect on macrophage differentiation;PID BioCarta;100169 |
Pathway | Endothelins;PID Curated;200004 |
Pathway | B cell activation;PANTHER;P00010 |
Pathway | Presenilin action in Notch and Wnt signaling;PID Curated;200052 |
Pathway | Downstream signaling in naive CD8+ T cells;PID Curated;200184 |
Pathway | keratinocyte differentiation;PID BioCarta;100119 |
Pathway | toll-like receptor pathway;PID BioCarta;100013 |
Pathway | Trk receptor signaling mediated by the MAPK pathway;PID Curated;200182 |
Pathway | Leishmaniasis;KEGG PATHWAY;hsa05140 |
Pathway | AP-1 transcription factor network;PID Curated;200118 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Pathway | angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling;PID BioCarta;100236 |
Pathway | bcr signaling pathway;PID BioCarta;100227 |
Pathway | Fc-epsilon receptor I signaling in mast cells;PID Curated;200003 |
Pathway | t cell receptor signaling pathway;PID BioCarta;100022 |
Pathway | Huntington disease;PANTHER;P00029 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | bone remodeling;PID BioCarta;100052 |
Pathway | Chagas disease;KEGG PATHWAY;hsa05142 |
Pathway | nerve growth factor pathway (ngf);PID BioCarta;100096 |
Pathway | S1P2 pathway;PID Curated;200181 |
Pathway | Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620 |
Pathway | FOXA1 transcription factor network;PID Curated;200194 |
Pathway | tpo signaling pathway;PID BioCarta;100012 |
Pathway | RhoA signaling pathway;PID Curated;200007 |
Pathway | repression of pain sensation by the transcriptional regulator dream;PID BioCarta;100186 |
Pathway | cadmium induces dna synthesis and proliferation in macrophages;PID BioCarta;100209 |
Pathway | IL6-mediated signaling events;PID Curated;200124 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | role of egf receptor transactivation by gpcrs in cardiac hypertrophy;PID BioCarta;100221 |
Pathway | GMCSF-mediated signaling events;PID Curated;200015 |
Pathway | FGF signaling pathway;PID Curated;200189 |
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External Links |
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Links to Entrez Gene | 2353 |
Links to all GeneRIF Items | 2353 |
Links to iHOP | 2353 |
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Sequence Information |
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Nucleotide Sequence |
>2353 : length: 1143 atgatgttctcgggcttcaacgcagactacgaggcgtcatcctcccgctgcagcagcgcg tccccggccggggatagcctctcttactaccactcacccgcagactccttctccagcatg ggctcgcctgtcaacgcgcaggacttctgcacggacctggccgtctccagtgccaacttc attcccacggtcactgccatctcgaccagtccggacctgcagtggctggtgcagcccgcc ctcgtctcctccgtggccccatcgcagaccagagcccctcaccctttcggagtccccgcc ccctccgctggggcttactccagggctggcgttgtgaagaccatgacaggaggccgagcg cagagcattggcaggaggggcaaggtggaacagttatctccagaagaagaagagaaaagg agaatccgaagggaaaggaataagatggctgcagccaaatgccgcaaccggaggagggag ctgactgatacactccaagcggagacagaccaactagaagatgagaagtctgctttgcag accgagattgccaacctgctgaaggagaaggaaaaactagagttcatcctggcagctcac cgacctgcctgcaagatccctgatgacctgggcttcccagaagagatgtctgtggcttcc cttgatctgactgggggcctgccagaggttgccaccccggagtctgaggaggccttcacc ctgcctctcctcaatgaccctgagcccaagccctcagtggaacctgtcaagagcatcagc agcatggagctgaagaccgagccctttgatgacttcctgttcccagcatcatccaggccc agtggctctgagacagcccgctccgtgccagacatggacctatctgggtccttctatgca gcagactgggagcctctgcacagtggctccctggggatggggcccatggccacagagctg gagcccctgtgcactccggtggtcacctgtactcccagctgcactgcttacacgtcttcc ttcgtcttcacctaccccgaggctgactccttccccagctgtgcagctgcccaccgcaag ggcagcagcagcaatgagccttcctctgactcgctcagctcacccacgctgctggccctg tga |
Protein Sequence |
>2353 : length: 380 MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF IPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRA QSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQ TEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFT LPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYA ADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRK GSSSNEPSSDSLSSPTLLAL |