| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 3082 |
Name | HGF |
Synonym | DFNB39|F-TCF|HGFB|HPTA|SF;hepatocyte growth factor (hepapoietin A; scatter factor);HGF;hepatocyte growth factor (hepapoietin A; scatter factor) |
Definition | fibroblast-derived tumor cytotoxic factor|hepatocyte growth factor|hepatopoeitin-A|hepatopoietin-A|lung fibroblast-derived mitogen |
Position | 7q21.1 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | Gene transfer of hepatocyte growth factor with prostacyclin synthase in severe pulmonary hypertension of rats. |
PH | [In vivo transfection of hepatocyte growth factor gene induces pulmonary angiogenesis in rabbits with hyperkinetic pulmonary hypertension]. |
| More detail of all Human literatures about HGF | |
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Pathways and Diseases |
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Pathway | Melanoma;KEGG PATHWAY;hsa05218 |
Pathway | Signaling events mediated by TCPTP;PID Curated;200065 |
Pathway | Malaria;KEGG PATHWAY;hsa05144 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | Arf6 signaling events;PID Curated;200060 |
Pathway | Syndecan-1-mediated signaling events;PID Curated;200134 |
Pathway | Stabilization and expansion of the E-cadherin adherens junction;PID Curated;200155 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Renal cell carcinoma;KEGG PATHWAY;hsa05211 |
Pathway | FGF signaling pathway;PID Curated;200189 |
Disease | blood pressure, arterial;GAD |
Disease | hypertension;GAD |
Disease | Deafness, autosomal recessive 39;OMIM |
Disease | VISION;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | carotid atherosclerosis;GAD |
Disease | Myopia;GAD |
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External Links |
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Links to Entrez Gene | 3082 |
Links to all GeneRIF Items | 3082 |
Links to iHOP | 3082 |
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Sequence Information |
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Nucleotide Sequence |
>3082 : length: 2187 atgtgggtgaccaaactcctgccagccctgctgctgcagcatgtcctcctgcatctcctc ctgctccccatcgccatcccctatgcagagggacaaaggaaaagaagaaatacaattcat gaattcaaaaaatcagcaaagactaccctaatcaaaatagatccagcactgaagataaaa accaaaaaagtgaatactgcagaccaatgtgctaatagatgtactaggaataaaggactt ccattcacttgcaaggcttttgtttttgataaagcaagaaaacaatgcctctggttcccc ttcaatagcatgtcaagtggagtgaaaaaagaatttggccatgaatttgacctctatgaa aacaaagactacattagaaactgcatcattggtaaaggacgcagctacaagggaacagta tctatcactaagagtggcatcaaatgtcagccctggagttccatgataccacacgaacac agctttttgccttcgagctatcggggtaaagacctacaggaaaactactgtcgaaatcct cgaggggaagaagggggaccctggtgtttcacaagcaatccagaggtacgctacgaagtc tgtgacattcctcagtgttcagaagttgaatgcatgacctgcaatggggagagttatcga ggtctcatggatcatacagaatcaggcaagatttgtcagcgctgggatcatcagacacca caccggcacaaattcttgcctgaaagatatcccgacaagggctttgatgataattattgc cgcaatcccgatggccagccgaggccatggtgctatactcttgaccctcacacccgctgg gagtactgtgcaattaaaacatgcgctgacaatactatgaatgacactgatgttcctttg gaaacaactgaatgcatccaaggtcaaggagaaggctacaggggcactgtcaataccatt tggaatggaattccatgtcagcgttgggattctcagtatcctcacgagcatgacatgact cctgaaaatttcaagtgcaaggacctacgagaaaattactgccgaaatccagatgggtct gaatcaccctggtgttttaccactgatccaaacatccgagttggctactgctcccaaatt ccaaactgtgatatgtcacatggacaagattgttatcgtgggaatggcaaaaattatatg ggcaacttatcccaaacaagatctggactaacatgttcaatgtgggacaagaacatggaa gacttacatcgtcatatcttctgggaaccagatgcaagtaagctgaatgagaattactgc cgaaatccagatgatgatgctcatggaccctggtgctacacgggaaatccactcattcct tgggattattgccctatttctcgttgtgaaggtgataccacacctacaatagtcaattta gaccatcccgtaatatcttgtgccaaaacgaaacaattgcgagttgtaaatgggattcca acacgaacaaacataggatggatggttagtttgagatacagaaataaacatatctgcgga ggatcattgataaaggagagttgggttcttactgcacgacagtgtttcccttctcgagac ttgaaagattatgaagcttggcttggaattcatgatgtccacggaagaggagatgagaaa tgcaaacaggttctcaatgtttcccagctggtatatggccctgaaggatcagatctggtt ttaatgaagcttgccaggcctgctgtcctggatgattttgttagtacgattgatttacct aattatggatgcacaattcctgaaaagaccagttgcagtgtttatggctggggctacact ggattgatcaactatgatggcctattacgagtggcacatctctatataatgggaaatgag aaatgcagccagcatcatcgagggaaggtgactctgaatgagtctgaaatatgtgctggg gctgaaaagattggatcaggaccatgtgagggggattatggtggcccacttgtttgtgag caacataaaatgagaatggttcttggtgtcattgttcctggtcgtggatgtgccattcca aatcgtcctggtatttttgtccgagtagcatattatgcaaaatggatacacaaaattatt ttaacatataaggtaccacagtcatag |
Protein Sequence |
>3082 : length: 728 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPL ETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGS ESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNME DLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNL DHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRD LKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLP NYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAG AEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII LTYKVPQS |