| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 3127 |
Name | HLA-DRB5 |
Synonym | HLA-DRB;major histocompatibility complex, class II, DR beta 5;HLA-DRB5;major histocompatibility complex, class II, DR beta 5 |
Definition | DR beta-5|DR-9|DR2-beta-2|DR9|HLA class II histocompatibility antigen, DR beta 5 chain|HLA class II histocompatibility antigen, DR-5 beta chain|HLA class II histocompatibility antigen, DRB1-9 beta chain|MHC HLA-DR-beta cell surface glycoprotein|MHC HLA-DR |
Position | 6p21.3 |
Gene Type | protein-coding |
|
PAH Type |
Description |
PAH | "HLA-DRw52 and -DRw6, initial sPAP > 60 mmHg, mRAP, and shorter time between SSc onset and observed PAH were associated with decreased survival; however, methodologic quality of study reporting was variable. Prognostic factor research is needed using current methodologic standards." |
| More detail of all Human literatures about HLA-DRB5 | |
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Pathways and Diseases |
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Pathway | Antigen processing and presentation;KEGG PATHWAY;hsa04612 |
Pathway | Type I diabetes mellitus;KEGG PATHWAY;hsa04940 |
Pathway | Allograft rejection;KEGG PATHWAY;hsa05330 |
Pathway | Asthma;KEGG PATHWAY;hsa05310 |
Pathway | Viral myocarditis;KEGG PATHWAY;hsa05416 |
Pathway | Staphylococcus aureus infection;KEGG PATHWAY;hsa05150 |
Pathway | Systemic lupus erythematosus;KEGG PATHWAY;hsa05322 |
Pathway | Hematopoietic cell lineage;KEGG PATHWAY;hsa04640 |
Pathway | Cell adhesion molecules (CAMs);KEGG PATHWAY;hsa04514 |
Pathway | Graft-versus-host disease;KEGG PATHWAY;hsa05332 |
Pathway | Leishmaniasis;KEGG PATHWAY;hsa05140 |
Pathway | Toxoplasmosis;KEGG PATHWAY;hsa05145 |
Pathway | Phagosome;KEGG PATHWAY;hsa04145 |
Pathway | Autoimmune thyroid disease;KEGG PATHWAY;hsa05320 |
Pathway | Intestinal immune network for IgA production;KEGG PATHWAY;hsa04672 |
Disease | echinococcosis;GAD |
Disease | tuberculosis;GAD |
Disease | schistosomiasis;GAD |
Disease | IMMUNE;GAD |
Disease | malaria;GAD |
Disease | periodontitis;GAD |
Disease | INFECTION;GAD |
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External Links |
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Links to Entrez Gene | 3127 |
Links to all GeneRIF Items | 3127 |
Links to iHOP | 3127 |
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Sequence Information |
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Nucleotide Sequence |
>3127 : length: 801 atggtgtgtctgaagctccctggaggttcctacatggcaaagctgacagtgacactgatg gtgctgagctccccactggctttggctggggacacccgaccacgtttcttgcagcaggat aagtatgagtgtcatttcttcaacgggacggagcgggtgcggttcctgcacagagacatc tataaccaagaggaggacttgcgcttcgacagcgacgtgggggagtaccgggcggtgacg gagctggggcggcctgacgctgagtactggaacagccagaaggacttcctggaagacagg cgcgccgcggtggacacctactgcagacacaactacggggttggtgagagcttcacagtg cagcggcgagttgagcctaaggtgactgtgtatcctgcaaggacccagaccctgcagcac cacaacctcctggtctgctctgtgaatggtttctatccaggcagcattgaagtcaggtgg ttccggaacagccaggaagagaaggctggggtggtgtccacaggcctgattcagaatgga gactggaccttccagaccctggtgatgctggaaacagttcctcgaagtggagaggtttac acctgccaagtggagcacccaagcgtgacgagccctctcacagtggaatggagagcacag tctgaatctgcacagagcaagatgctgagtggagtcgggggctttgtgctgggcctgctc ttccttggggccgggctattcatctacttcaagaatcagaaagggcactctggacttcac ccaacaggactcgtgagctga |
Protein Sequence |
>3127 : length: 266 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL FLGAGLFIYFKNQKGHSGLHPTGLVS |