| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 3295 |
Name | HSD17B4 |
Synonym | DBP|MFE-2|MPF-2|PRLTS1|SDR8C1;hydroxysteroid (17-beta) dehydrogenase 4;HSD17B4;hydroxysteroid (17-beta) dehydrogenase 4 |
Definition | 17-beta-HSD 4|17-beta-HSD IV|17-beta-hydroxysteroid dehydrogenase 4|17beta-estradiol dehydrogenase type IV|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase|D-3-hydroxyacyl-CoA dehydratase|D-bifunctional protein, peroxisomal|beta-h |
Position | 5q21 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | Personal communication to Dr. Eric D. Austin. |
| More detail of all Human literatures about HSD17B4 | |
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Pathways and Diseases |
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Pathway | Primary bile acid biosynthesis;KEGG PATHWAY;hsa00120 |
Pathway | Beta-oxidation of pristanoyl-CoA;PID Reactome;500820 |
Pathway | mechanism of gene regulation by peroxisome proliferators via ppara;PID BioCarta;100066 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
Pathway | Peroxisome;KEGG PATHWAY;hsa04146 |
Pathway | Beta-oxidation of very long chain fatty acids;PID Reactome;500821 |
Pathway | Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol;PID Reactome;500828 |
Pathway | Peroxisomal lipid metabolism;PID Reactome;500818 |
Disease | Peroxisomal beta-oxidation enzyme deficiency;KEGG DISEASE;H00407 |
Disease | Peroxisomal diseases;KEGG DISEASE |
Disease | Congenital abnormality;FunDO |
Disease | Genetic disorders;KEGG DISEASE |
Disease | D-bifunctional protein deficiency;OMIM |
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External Links |
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Links to Entrez Gene | 3295 |
Links to all GeneRIF Items | 3295 |
Links to iHOP | 3295 |
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Sequence Information |
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Nucleotide Sequence |
>3295 : length: 2211 atgggctcaccgctgaggttcgacgggcgggtggtactggtcaccggcgcgggggcagga ttgggccgagcctatgccctggcttttgcagaaagaggagcgttagttgttgtgaatgat ttgggaggggacttcaaaggagttggtaaaggctccttagctgctgataaggttgttgaa gaaataagaaggagaggtggaaaagcagtggccaactatgattcagtggaagaaggagag aaggttgtgaagacagccctggatgcttttggaagaatagatgttgtggtcaacaatgct ggaattctgagggatcgttcctttgctaggataagtgatgaagactgggatataatccac agagttcatttgcggggttcattccaagtgacacgggcagcatgggaacacatgaagaaa cagaagtatggaaggattattatgacttcatcagcttcaggaatatatggcaactttggc caggccaattatagtgctgcaaagttgggtcttctgggccttgcaaattctcttgcaatt gaaggcaggaaaagcaacattcattgtaacaccattgctcctaatgcgggatcacggatg actcagacagttatgcctgaagatcttgtggaagccctgaagccagagtatgtggcacct cttgtcctttggctttgtcacgagagttgtgaggagaatggtggcttgtttgaggttgga gcaggatggattggaaaattacgctgggagcggactcttggagctattgtaagacaaaag aatcacccaatgactcctgaggcagtcaaggctaactggaagaagatctgtgactttgag aatgccagcaagcctcagagtatccaagaatcaactggcagtataattgaagttctgagt aaaatagattcagaaggaggagtttcagcaaatcatactagtcgtgcaacgtctacagca acatcaggatttgctggagctattggccagaaactccctccattttcttatgcttatacg gaactggaagctattatgtatgcccttggagtgggagcgtcaatcaaggatccaaaagat ttgaaatttatttatgaaggaagttctgatttctcctgtttgcccaccttcggagttatc ataggtcagaaatctatgatgggtggaggattagcagaaattcctggactttcaatcaac tttgcaaaggttcttcatggagagcagtacttagagttatataaaccacttcccagagca ggaaaattaaaatgtgaagcagttgttgctgatgtcctagataaaggatccggtgtagtg attattatggatgtctattcttattctgagaaggaacttatatgccacaatcagttctct ctctttcttgttggctctggaggctttggtggaaaacggacatcagacaaagtcaaggta gctgtagccatacctaatagacctcctgatgctgtacttacagataccacctctcttaat caggctgctttgtaccgcctcagtggagactggaatcccttacacattgatcctaacttt gctagtctagcaggttttgacaagcccatattacatggattatgtacatttggattttct gccaggcgtgtgttacagcagtttgcagataatgatgtgtcaagattcaaggcaattaag gctcgttttgcaaaaccagtatatccaggacaaactctacaaactgagatgtggaaggaa ggaaacagaattcattttcaaaccaaggtccaagaaactggagacattgtcatttcaaat gcatatgtggatcttgcaccaacatctggtacttcagctaagacaccctctgagggcggg aagcttcagagtacctttgtatttgaggaaataggacgccgcctaaaggatattgggcct gaggtggtgaagaaagtaaatgctgtatttgagtggcatataaccaaaggcggaaatatt ggggctaagtggactattgacctgaaaagtggttctggaaaagtgtaccaaggccctgca aaaggtgctgctgatacaacaatcatactttcagatgaagatttcatggaggtggtcctg ggcaagcttgaccctcagaaggcattctttagtggcaggctgaaggccagagggaacatc atgctgagccagaaacttcagatgattcttaaagactacgccaagctctga |
Protein Sequence |
>3295 : length: 736 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI MLSQKLQMILKDYAKL |