| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3295 |
Name | HSD17B4 |
Synonymous | DBP|MFE-2|MPF-2|PRLTS1|SDR8C1;hydroxysteroid (17-beta) dehydrogenase 4;HSD17B4;hydroxysteroid (17-beta) dehydrogenase 4 |
Definition | 17-beta-HSD 4|17-beta-HSD IV|17-beta-hydroxysteroid dehydrogenase 4|17beta-estradiol dehydrogenase type IV|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase|D-3-hydroxyacyl-CoA dehydratase|D-bifunctional protein, peroxisomal|beta-h |
Position | 5q21 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
|
Link to UCSC genome |
Matched SNP location |
dbSNP ID |
Regulatory information |
chr5:118788138-118972894 | chr5:118925916-118925916 | rs328678 | Single_Nucleotides|eQTL|HSD17B4, Motifs|PWM|STAT5A(homotetramer), Chromatin_Structure|DNase-seq|Hae |
|---|---|---|---|
Transcription Factors [Top] |
|
Regulation From TransFac database |
HSD17B4(h) --> peroxisomal multifunctional enzyme type 2(h) (expression). | HSD17B4(h) --> peroxisomal multifunctional enzyme type 2(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
3 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 309 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 663 | N6-acetyllysine (By similarity). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr5 |
Promoter: 118814624 - 118816624 | Agilent_014791 |
chr5 |
Promoter: 118814624 - 118816624 | GSE27584 |
chr5 |
Promoter: 118814624 - 118816624 | Agilent_014791_44K |
chr5 |
Promoter: 118814624 - 118816624 | PMID:15172987 |