| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 3554 |
Name | IL1R1 |
Synonym | CD121A|D2S1473|IL-1R-alpha|IL1R|IL1RA|P80;interleukin 1 receptor, type I;IL1R1;interleukin 1 receptor, type I |
Definition | CD121 antigen-like family member A|IL-1R-1|IL-1RT-1|IL-1RT1|antigen CD121a|interleukin 1 receptor alpha, type I|interleukin receptor 1|interleukin-1 receptor alpha|interleukin-1 receptor type 1|interleukin-1 receptor type I |
Position | 2q12 |
Gene Type | protein-coding |
|
PAH Type |
Description |
PAH | ApoE(-/-)/IL-1R1(-/-) mice showed an even more severe pulmonary arterial hypertension phenotype. |
PAH | ApoE(-/-)/IL-1R1(-/-) mice showed an even more severe pulmonary arterial hypertension phenotype. |
| More detail of all Mouse literatures about IL1R1 | |
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Pathways and Diseases |
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Pathway | Amoebiasis;KEGG PATHWAY;hsa05146 |
Pathway | Apoptosis;KEGG PATHWAY;hsa04210 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | signal transduction through il1r;PID BioCarta;100132 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Hematopoietic cell lineage;KEGG PATHWAY;hsa04640 |
Pathway | Interleukin-1 signaling;PID Reactome;500490 |
Pathway | IL12-mediated signaling events;PID Curated;200034 |
Pathway | nf-kb signaling pathway;PID BioCarta;100097 |
Pathway | IL1-mediated signaling events;PID Curated;200075 |
Disease | Hepatitis;FunDO |
Disease | Lung cancer;FunDO |
Disease | Degenerative disc disease;FunDO |
Disease | thryoiditis, subacute granulomatous;GAD |
Disease | ankylosing spondylitis;GAD |
Disease | Breast cancer;FunDO |
Disease | Mitral valve disease;FunDO |
Disease | bone loss;GAD |
Disease | IL-1RI;GAD |
Disease | H. pylori infection;GAD |
Disease | IMMUNE;GAD |
Disease | Rheumatoid arthritis;FunDO |
Disease | graft-versus-host disease;GAD |
Disease | METABOLIC;GAD |
Disease | periodontitis;GAD |
Disease | Schizophrenia;FunDO |
Disease | INFECTION;GAD |
Disease | Nephrosis;FunDO |
Disease | sepsis;GAD |
Disease | diabetes, type 1;GAD |
Disease | Coronary Artery Disease;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Bone mineral mass;GAD |
Disease | CANCER;GAD |
Disease | Endometriosis;FunDO |
Disease | bone mass;GAD |
Disease | Hodgkin lymphoma;GAD |
Disease | stomach cancer;GAD |
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External Links |
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Links to Entrez Gene | 3554 |
Links to all GeneRIF Items | 3554 |
Links to iHOP | 3554 |
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Sequence Information |
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Nucleotide Sequence |
>3554 : length: 1710 atgaaagtgttactcagacttatttgtttcatagctctactgatttcttctctggaggct gataaatgcaaggaacgtgaagaaaaaataattttagtgtcatctgcaaatgaaattgat gttcgtccctgtcctcttaacccaaatgaacacaaaggcactataacttggtataaagat gacagcaagacacctgtatctacagaacaagcctccaggattcatcaacacaaagagaaa ctttggtttgttcctgctaaggtggaggattcaggacattactattgcgtggtaagaaat tcatcttactgcctcagaattaaaataagtgcaaaatttgtggagaatgagcctaactta tgttataatgcacaagccatatttaagcagaaactacccgttgcaggagacggaggactt gtgtgcccttatatggagttttttaaaaatgaaaataatgagttacctaaattacagtgg tataaggattgcaaacctctacttcttgacaatatacactttagtggagtcaaagatagg ctcatcgtgatgaatgtggctgaaaagcatagagggaactatacttgtcatgcatcctac acatacttgggcaagcaatatcctattacccgggtaatagaatttattactctagaggaa aacaaacccacaaggcctgtgattgtgagcccagctaatgagacaatggaagtagacttg ggatcccagatacaattgatctgtaatgtcaccggccagttgagtgacattgcttactgg aagtggaatgggtcagtaattgatgaagatgacccagtgctaggggaagactattacagt gtggaaaatcctgcaaacaaaagaaggagtaccctcatcacagtgcttaatatatcggaa attgaaagtagattttataaacatccatttacctgttttgccaagaatacacatggtata gatgcagcatatatccagttaatatatccagtcactaatttccagaagcacatgattggt atatgtgtcacgttgacagtcataattgtgtgttctgttttcatctataaaatcttcaag attgacattgtgctttggtacagggattcctgctatgattttctcccaataaaagcttca gatggaaagacctatgacgcatatatactgtatccaaagactgttggggaagggtctacc tctgactgtgatatttttgtgtttaaagtcttgcctgaggtcttggaaaaacagtgtgga tataagctgttcatttatggaagggatgactacgttggggaagacattgttgaggtcatt aatgaaaacgtaaagaaaagcagaagactgattatcattttagtcagagaaacatcaggc ttcagctggctgggtggttcatctgaagagcaaatagccatgtataatgctcttgttcag gatggaattaaagttgtcctgcttgagctggagaaaatccaagactatgagaaaatgcca gaatcgattaaattcattaagcagaaacatggggctatccgctggtcaggggactttaca cagggaccacagtctgcaaagacaaggttctggaagaatgtcaggtaccacatgccagtc cagcgacggtcaccttcatctaaacaccagttactgtcaccagccactaaggagaaactg caaagagaggctcacgtgcctctcgggtag |
Protein Sequence |
>3554 : length: 569 MKVLLRLICFIALLISSLEADKCKEREEKIILVSSANEIDVRPCPLNPNEHKGTITWYKD DSKTPVSTEQASRIHQHKEKLWFVPAKVEDSGHYYCVVRNSSYCLRIKISAKFVENEPNL CYNAQAIFKQKLPVAGDGGLVCPYMEFFKNENNELPKLQWYKDCKPLLLDNIHFSGVKDR LIVMNVAEKHRGNYTCHASYTYLGKQYPITRVIEFITLEENKPTRPVIVSPANETMEVDL GSQIQLICNVTGQLSDIAYWKWNGSVIDEDDPVLGEDYYSVENPANKRRSTLITVLNISE IESRFYKHPFTCFAKNTHGIDAAYIQLIYPVTNFQKHMIGICVTLTVIIVCSVFIYKIFK IDIVLWYRDSCYDFLPIKASDGKTYDAYILYPKTVGEGSTSDCDIFVFKVLPEVLEKQCG YKLFIYGRDDYVGEDIVEVINENVKKSRRLIIILVRETSGFSWLGGSSEEQIAMYNALVQ DGIKVVLLELEKIQDYEKMPESIKFIKQKHGAIRWSGDFTQGPQSAKTRFWKNVRYHMPV QRRSPSSKHQLLSPATKEKLQREAHVPLG |