Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3554

Name

IL1R1

Synonymous

CD121A|D2S1473|IL-1R-alpha|IL1R|IL1RA|P80;interleukin 1 receptor, type I;IL1R1;interleukin 1 receptor, type I

Definition

CD121 antigen-like family member A|IL-1R-1|IL-1RT-1|IL-1RT1|antigen CD121a|interleukin 1 receptor alpha, type I|interleukin receptor 1|interleukin-1 receptor alpha|interleukin-1 receptor type 1|interleukin-1 receptor type I

Position

2q12

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for IL1R1

Transcription Factors   [Top]

Regulation From TransFac database

IL-1RI(h) + IRAK-2(h) <==> IL-1RI(h):IRAK-2(h) (binding)
IL-1beta(h) + IL-1RI(h) <==> IL-1beta(h):IL-1RI(h) (binding)
IL-1RI(h) + IL-1RAcP(h) + IRAK1(h) <==> IL-1RI(h):IL-1RAcP(h):IRAK1(h) (binding)
IL-1RI(h) + RhoA(h) <==> IL-1RI(h):RhoA(h) (binding)
IL-1RI(h) + Rac1(h) <==> IL-1RI(h):Rac1(h) (binding)
IL-1RI(h) + IL-1RAcP(m) + tollip(m) <==> IL-1RI(h):IL-1RAcP(m):tollip(m) (binding)
IL-1RI(h) + TRAM(h) <==> IL-1RI(h):TRAM(h) (binding)
IL-1beta(h) + IL-1RI(h) + MyD88(h) + IRAK-4(h) + IRAK1(h) + TRAF6(h) <==> IL-1beta(h):IL-1RI(h):MyD88(h):IRAK-4(h):IRAK1(h):TRAF6(h) (binding)
IL-1RI(h) + MyD88(h) <==> IL-1RI(h):MyD88(h) (binding)
IL-1RI(h) + TRAF6(h) + IRAK1(h) <==> IL-1RI(h):TRAF6(h):IRAK1(h) (binding)
IL-1RI(h) + SIGIRR(h) <==> IL-1RI(h):SIGIRR(h) (binding)
TILRR(h) + IL-1RI(h) <==> TILRR(h):IL-1RI(h) (binding)
IL1R1(h) --> IL-1RI(h) (expression).
IL1R1(h) --> IL-1RI(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

100N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
193N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
233N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
249N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
263N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
297N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
556Phosphothreonine (by PKC) (Bysimilarity).Swiss-Prot 53.0
496Phosphotyrosine9821957Phospho.ELM 6.0

Methylation Profile   [Top]

There is no record for IL1R1



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