Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3627

Name

CXCL10

Synonym

C7|IFI10|INP10|IP-10|SCYB10|crg-2|gIP-10|mob-1;chemokine (C-X-C motif) ligand 10;CXCL10;chemokine (C-X-C motif) ligand 10

Definition

10 kDa interferon gamma-induced protein|C-X-C motif chemokine 10|gamma IP10|gamma-IP10|interferon-inducible cytokine IP-10|protein 10 from interferon (gamma)-induced cell line|small inducible cytokine subfamily B (Cys-X-Cys), member 10|small-inducible cyt

Position

4q21

Gene Type

protein-coding

PAH Type

Description

PAH

CXC-chemokine ligand 10 in idiopathic pulmonary arterial hypertension: marker of improved survival.
More detail of all Human literatures about CXCL10

Pathways and Diseases

Pathway

Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620

Pathway

Signaling by GPCR;Reactome;REACT:14797

Pathway

Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060

Pathway

RIG-I-like receptor signaling pathway;KEGG PATHWAY;hsa04622

Pathway

Chemokine signaling pathway;KEGG PATHWAY;hsa04062

Pathway

Cytosolic DNA-sensing pathway;KEGG PATHWAY;hsa04623

Pathway

Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031

Pathway

CXCR3-mediated signaling events;PID Curated;200150

Disease

Autoimmune disease;FunDO

Disease

Primary biliary cirrhosis;FunDO

Disease

Hypothyroidism;FunDO

Disease

Pre-Eclampsia;FunDO

Disease

Pancreatitis;FunDO

Disease

Chronic rejection of renal transplant;FunDO

Disease

Infection;FunDO

Disease

Prostate cancer;FunDO

Disease

Uterine cancer;FunDO

Disease

Asthma;FunDO

Disease

Ulcerative colitis;FunDO

Disease

Thyroid gland disease;FunDO

Disease

Liver disease;FunDO

Disease

Systemic infection;FunDO

Disease

Hepatitis C;FunDO

Disease

Chronic obstructive airway disease;FunDO

Disease

Atherosclerosis;FunDO

External Links

Links to Entrez Gene

3627

Links to all GeneRIF Items

3627

Links to iHOP

3627

Sequence Information

Nucleotide Sequence

>3627 : length: 297
atgaatcaaactgccattctgatttgctgccttatctttctgactctaagtggcattcaa
ggagtacctctctctagaactgtacgctgtacctgcatcagcattagtaatcaacctgtt
aatccaaggtctttagaaaaacttgaaattattcctgcaagccaattttgtccacgtgtt
gagatcattgctacaatgaaaaagaagggtgagaagagatgtctgaatccagaatcgaag
gccatcaagaatttactgaaagcagttagcaaggaaaggtctaaaagatctccttaa

Protein Sequence

>3627 : length: 98
MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRV
EIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP



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