| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 4035 |
Name | LRP1 |
Synonym | A2MR|APOER|APR|CD91|IGFBP3R|LRP|LRP1A|TGFBR5;low density lipoprotein receptor-related protein 1;LRP1;low density lipoprotein receptor-related protein 1 |
Definition | LRP-1|TbetaR-V/LRP-1/IGFBP-3 receptor|alpha-2-macroglobulin receptor|apolipoprotein E receptor|prolow-density lipoprotein receptor-related protein 1|type V tgf-beta receptor |
Position | 12q13.3 |
Gene Type | protein-coding |
|
PAH Type |
Description |
PH | Supplemental Table 1: A list of genes and functional categories that comprises a PHrelevant gene module (PH-module). |
| More detail of all Human literatures about LRP1 | |
|
Pathways and Diseases |
|
Pathway | amb2 Integrin signaling;PID Curated;200108 |
Pathway | PDGFR-beta signaling pathway;PID Curated;200127 |
Pathway | Malaria;KEGG PATHWAY;hsa05144 |
Pathway | Alzheimer's disease;KEGG PATHWAY;hsa05010 |
Pathway | Alzheimer disease-presenilin pathway;PANTHER;P00004 |
Disease | Lp(a);GAD |
Disease | atherosclerosis, coronary;GAD |
Disease | breast cancer;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | cerebral amyloid angiopathy;GAD |
Disease | CANCER;GAD |
Disease | Cancer;FunDO |
Disease | METABOLIC;GAD |
Disease | thromboembolism, venous;GAD |
Disease | HIV infection;FunDO |
Disease | Alzheimer's disease;FunDO |
Disease | Alzheimer's disease;GAD |
Disease | NEUROLOGICAL;GAD |
Disease | Atherosclerosis;FunDO |
|
External Links |
|
Links to Entrez Gene | 4035 |
Links to all GeneRIF Items | 4035 |
Links to iHOP | 4035 |
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Sequence Information |
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Nucleotide Sequence |
>4035 : length: 13635 atgctgaccccgccgttgctcctgctgctgcccctgctctcagctctggtcgcggcggct atcgacgcccctaagacttgcagccccaagcagtttgcctgcagagatcaaataacctgt atctcaaagggctggcggtgcgacggtgagagggactgcccagacggatctgacgaggcc cctgagatttgtccacagagtaaggcccagcgatgccagccaaacgagcataactgcctg ggtactgagctgtgtgttcccatgtcccgcctctgcaatggggtccaggactgcatggac ggctcagatgaggggccccactgccgagagctccaaggcaactgctctcgcctgggctgc cagcaccattgtgtccccacactcgatgggcccacctgctactgcaacagcagctttcag cttcaggcagatggcaagacctgcaaagattttgatgagtgctcagtgtacggcacctgc agccagctatgcaccaacacagacggctccttcatatgtggctgtgttgaaggatacctc ctgcagccggataaccgctcctgcaaggccaagaacgagccagtagaccggccccctgtg ctgttgatagccaactcccagaacatcttggccacgtacctgagtggggcccaggtgtct accatcacacctacgagcacgcggcagaccacagccatggacttcagctatgccaacgag accgtatgctgggtgcatgttggggacagtgctgctcagacgcagctcaagtgtgcccgc atgcctggcctaaagggcttcgtggatgagcacaccatcaacatctccctcagtctgcac cacgtggaacagatggccatcgactggctgacaggcaacttctactttgtggatgacatc gatgataggatctttgtctgcaacagaaatggggacacatgtgtcacattgctagacctg gaactctacaaccccaagggcattgccctggaccctgccatggggaaggtgtttttcact gactatgggcagatcccaaaggtggaacgctgtgacatggatgggcagaaccgcaccaag ctcgtcgacagcaagattgtgtttcctcatggcatcacgctggacctggtcagccgcctt gtctactgggcagatgcctatctggactatattgaagtggtggactatgagggcaagggc cgccagaccatcatccagggcatcctgattgagcacctgtacggcctgactgtgtttgag aattatctctatgccaccaactcggacaatgccaatgcccagcagaagacgagtgtgatc cgtgtgaaccgctttaacagcaccgagtaccaggttgtcacccgggtggacaagggtggt gccctccacatctaccaccagaggcgtcagccccgagtgaggagccatgcctgtgaaaac gaccagtatgggaagccgggtggctgctctgacatctgcctgctggccaacagccacaag gcgcggacctgccgctgccgttccggcttcagcctgggcagtgacgggaagtcatgcaag aagccggagcatgagctgttcctcgtgtatggcaagggccggccaggcatcatccggggc atggatatgggggccaaggtcccggatgagcacatgatccccattgaaaacctcatgaac ccccgagccctggacttccacgctgagaccggcttcatctactttgccgacaccaccagc tacctcattggccgccagaagattgatggcactgagcgggagaccatcctgaaggacggc atccacaatgtggagggtgtggccgtggactggatgggagacaatctgtactggacggac gatgggcccaaaaagacaatcagcgtggccaggctggagaaagctgctcagacccgcaag actttaatcgagggcaaaatgacacaccccagggctattgtggtggatccactcaatggg tggatgtactggacagactgggaggaggaccccaaggacagtcggcgtgggcggctggag agggcgtggatggatggctcacaccgagacatctttgtcacctccaagacagtgctttgg cccaatgggctaagcctggacatcccggctgggcgcctctactgggtggatgccttctac gaccgcatcgagacgatactgctcaatggcacagaccggaagattgtgtatgaaggtcct gagctgaaccacgcctttggcctgtgtcaccatggcaactacctcttctggactgagtat cggagtggcagtgtctaccgcttggaacggggtgtaggaggcgcaccccccactgtgacc cttctgcgcagtgagcggccccccatctttgagatccgaatgtatgatgcccagcagcag caagttggcaccaacaaatgccgggtgaacaatggcggctgcagcagcctgtgcttggcc acccctgggagccgccagtgcgcctgtgctgaggaccaggtgttggacgcagacggcgtc acttgcttggcgaacccatcctacgtgcctccaccccagtgccagccaggcgagtttgcc tgtgccaacagccgctgcatccaggagcgctggaagtgtgacggagacaacgattgcctg gacaacagtgatgaggccccagccctctgccatcagcacacctgcccctcggaccgattc aagtgcgagaacaaccggtgcatccccaaccgctggctctgcgacggggacaatgactgt gggaacagtgaagatgagtccaatgccacttgttcagcccgcacctgcccccccaaccag ttctcctgtgccagtggccgctgcatccccatctcctggacgtgtgatctggatgacgac tgtggggaccgctctgatgagtctgcttcgtgtgcctatcccacctgcttccccctgact cagtttacctgcaacaatggcagatgtatcaacatcaactggagatgcgacaatgacaat gactgtggggacaacagtgacgaagccggctgcagccactcctgttctagcacccagttc aagtgcaacagcgggcgttgcatccccgagcactggacctgcgatggggacaatgactgc ggagactacagtgatgagacacacgccaactgcaccaaccaggccacgaggccccctggt ggctgccacactgatgagttccagtgccggctggatggactatgcatccccctgcggtgg cgctgcgatggggacactgactgcatggactccagcgatgagaagagctgtgagggagtg acccacgtctgcgatcccagtgtcaagtttggctgcaaggactcagctcggtgcatcagc aaagcgtgggtgtgtgatggcgacaatgactgtgaggataactcggacgaggagaactgc gagtccctggcctgcaggccaccctcgcacccttgtgccaacaacacctcagtctgcctg ccccctgacaagctgtgtgatggcaacgacgactgtggcgacggctcagatgagggcgag ctctgcgaccagtgctctctgaataacggtggctgcagccacaactgctcagtggcacct ggcgaaggcattgtgtgttcctgccctctgggcatggagctggggcccgacaaccacacc tgccagatccagagctactgtgccaagcatctcaaatgcagccaaaagtgcgaccagaac aagttcagcgtgaagtgctcctgctacgagggctgggtcctggaacctgacggcgagagc tgccgcagcctggaccccttcaagccgttcatcattttctccaaccgccatgaaatccgg cgcatcgatcttcacaaaggagactacagcgtcctggtgcccggcctgcgcaacaccatc gccctggacttccacctcagccagagcgccctctactggaccgacgtggtggaggacaag atctaccgcgggaagctgctggacaacggagccctgactagtttcgaggtggtgattcag tatggcctggccacacccgagggcctggctgtagactggattgcaggcaacatctactgg gtggagagtaacctggatcagatcgaggtggccaagctggatgggaccctccggaccacc ctgctggccggtgacattgagcacccaagggcaatcgcactggatccccgggatgggatc ctgttttggacagactgggatgccagcctgccccgcattgaggcagcctccatgagtggg gctgggcgccgcaccgtgcaccgggagaccggctctgggggctggcccaacgggctcacc gtggactacctggagaagcgcatcctttggattgacgccaggtcagatgccatttactca gcccgttacgacggctctggccacatggaggtgcttcggggacacgagttcctgtcgcac ccgtttgcagtgacgctgtacgggggggaggtctactggactgactggcgaacaaacaca ctggctaaggccaacaagtggaccggccacaatgtcaccgtggtacagaggaccaacacc cagccctttgacctgcaggtgtaccacccctcccgccagcccatggctcccaatccctgt gaggccaatgggggccagggcccctgctcccacctgtgtctcatcaactacaaccggacc gtgtcctgcgcctgcccccacctcatgaagctccacaaggacaacaccacctgctatgag tttaagaagttcctgctgtacgcacgtcagatggagatccgaggtgtggacctggatgct ccctactacaactacatcatctccttcacggtgcccgacatcgacaacgtcacagtgcta gactacgatgcccgcgagcagcgtgtgtactggtctgacgtgcggacacaggccatcaag cgggccttcatcaacggcacaggcgtggagacagtcgtctctgcagacttgccaaatgcc cacgggctggctgtggactgggtctcccgaaacctgttctggacaagctatgacaccaat aagaagcagatcaatgtggcccggctggatggctccttcaagaacgcagtggtgcagggc ctggagcagccccatggccttgtcgtccaccctctgcgtgggaagctctactggaccgat ggtgacaacatcagcatggccaacatggatggcagcaatcgcaccctgctcttcagtggc cagaagggccccgtgggcctggctattgacttccctgaaagcaaactctactggatcagc tccgggaaccataccatcaaccgctgcaacctggatgggagtgggctggaggtcatcgat gccatgcggagccagctgggcaaggccaccgccctggccatcatgggggacaagctgtgg tgggctgatcaggtgtcggaaaagatgggcacatgcagcaaggctgacggctcgggctcc gtggtccttcggaacagcaccaccctggtgatgcacatgaaggtctatgacgagagcatc cagctggaccataagggcaccaacccctgcagtgtcaacaacggtgactgctcccagctc tgcctgcccacgtcagagacgacccgctcctgcatgtgcacagccggctatagcctccgg agtggccagcaggcctgcgagggcgtaggttcctttctcctgtactctgtgcatgaggga atcaggggaattcccctggatcccaatgacaagtcagatgccctggtcccagtgtccggg acctcgctggctgtcggcatcgacttccacgctgaaaatgacaccatctactgggtggac atgggcctgagcacgatcagccgggccaagcgggaccagacgtggcgtgaagacgtggtg accaatggcattggccgtgtggagggcattgcagtggactggatcgcaggcaacatctac tggacagaccagggctttgatgtcatcgaggtcgcccggctcaatggctccttccgctac gtggtgatctcccagggtctagacaagccccgggccatcaccgtccacccggagaaaggg tacttgttctggactgagtggggtcagtatccgcgtattgagcggtctcggctagatggc acggagcgtgtggtgctggtcaacgtcagcatcagctggcccaacggcatctcagtggac taccaggatgggaagctgtactggtgcgatgcacggacagacaagattgaacggatcgac ctggagacaggtgagaaccgcgaggtggttctgtccagcaacaacatggacatgttttca gtgtctgtgtttgaggatttcatctactggagtgacaggactcatgccaacggctctatc aagcgcgggagcaaagacaatgccacagactccgtgcccctgcgaaccggcatcggcgtc cagcttaaagacatcaaagtcttcaaccgggaccggcagaaaggcaccaacgtgtgcgcg gtggccaatggcgggtgccagcagctgtgcctgtaccggggccgtgggcagcgggcctgc gcctgtgcccacgggatgctggctgaagacggagcatcgtgccgcgagtatgccggctac ctgctctactcagagcgcaccattctcaagagtatccacctgtcggatgagcgcaacctc aatgcgcccgtgcagcccttcgaggaccctgagcacatgaagaacgtcatcgccctggcc tttgactaccgggcaggcacctctccgggcacccccaatcgcatcttcttcagcgacatc cactttgggaacatccaacagatcaacgacgatggctccaggaggatcaccattgtggaa aacgtgggctccgtggaaggcctggcctatcaccgtggctgggacactctctattggaca agctacacgacatccaccatcacgcgccacacagtggaccagacccgcccaggggccttc gagcgtgagaccgtcatcactatgtctggagatgaccacccacgggccttcgttttggac gagtgccagaacctcatgttctggaccaactggaatgagcagcatcccagcatcatgcgg gcggcgctctcgggagccaatgtcctgacccttatcgagaaggacatccgtacccccaat ggcctggccatcgaccaccgtgccgagaagctctacttctctgacgccaccctggacaag atcgagcggtgcgagtatgacggctcccaccgctatgtgatcctaaagtcagagcctgtc caccccttcgggctggccgtgtatggggagcacattttctggactgactgggtgcggcgg gcagtgcagcgggccaacaagcacgtgggcagcaacatgaagctgctgcgcgtggacatc ccccagcagcccatgggcatcatcgccgtggccaacgacaccaacagctgtgaactctct ccatgccgaatcaacaacggtggctgccaggacctgtgtctgctcactcaccagggccat gtcaactgctcatgccgagggggccgaatcctccaggatgacctcacctgccgagcggtg aattcctcttgccgagcacaagatgagtttgagtgtgccaatggcgagtgcatcaacttc agcctgacctgcgacggcgtcccccactgcaaggacaagtccgatgagaagccatcctac tgcaactcccgccgctgcaagaagactttccggcagtgcagcaatgggcgctgtgtgtcc aacatgctgtggtgcaacggggccgacgactgtggggatggctctgacgagatcccttgc aacaagacagcctgtggtgtgggcgagttccgctgccgggacgggacctgcatcgggaac tccagccgctgcaaccagtttgtggattgtgaggacgcctcagatgagatgaactgcagt gccaccgactgcagcagctacttccgcctgggcgtgaagggcgtgctcttccagccctgc gagcggacctcactctgctacgcacccagctgggtgtgtgatggcgccaatgactgtggg gactacagtgatgagcgcgactgcccaggtgtgaaacgccccagatgccctctgaattac ttcgcctgccctagtgggcgctgcatccccatgagctggacgtgtgacaaagaggatgac tgtgaacatggcgaggacgagacccactgcaacaagttctgctcagaggcccagtttgag tgccagaaccatcgctgcatctccaagcagtggctgtgtgacggcagcgatgactgtggg gatggctcagacgaggctgctcactgtgaaggcaagacgtgcggcccctcctccttctcc tgccctggcacccacgtgtgcgtccccgagcgctggctctgtgacggtgacaaagactgt gctgatggtgcagacgagagcatcgcagctggttgcttgtacaacagcacttgtgacgac cgtgagttcatgtgccagaaccgccagtgcatccccaagcacttcgtgtgtgaccacgac cgtgactgtgcagatggctctgatgagtcccccgagtgtgagtacccgacctgcggcccc agtgagttccgctgtgccaatgggcgctgtctgagctcccgccagtgggagtgtgatggc gagaatgactgccacgaccagagtgacgaggctcccaagaacccacactgcaccagccaa gagcacaagtgcaatgcctcgtcacagttcctgtgcagcagtgggcgctgtgtggctgag gcactgctctgcaacggccaggatgactgtggcgacagctcggacgagcgtggctgccac atcaatgagtgtctcagccgcaagctcagtggctgcagccaggactgtgaggacctcaag atcggcttcaagtgccgctgtcgccctggcttccggctgaaggacgacggccggacgtgt gctgatgtggacgagtgcagcaccaccttcccctgcagccagcgctgcatcaacactcat ggcagctataagtgtctgtgtgtggagggctatgcaccccgcggcggcgacccccacagc tgcaaggctgtgactgacgaggaaccgtttctgatcttcgccaaccggtactacctgcgc aagctcaacctggacgggtccaactacacgttacttaagcagggcctgaacaacgccgtt gccttggattttgactaccgagagcagatgatctactggacagatgtgaccacccagggc agcatgatccgaaggatgcaccttaacgggagcaatgtgcaggtcctacaccgtacaggc ctcagcaaccccgatgggctggctgtggactgggtgggtggcaacctgtactggtgcgac aaaggccgggacaccatcgaggtgtccaagctcaatggggcctatcggacggtgctggtc agctctggcctccgtgagcccagggctctggtggtggatgtgcagaatgggtacctgtac tggacagactggggtgaccattcactgatcggccgcatcggcatggatgggtccagccgc agcgtcatcgtggacaccaagatcacatggcccaatggcctgacgctggactatgtcact gagcgcatctactgggccgacgcccgcgaggactacattgaatttgccagcctggatggc tccaatcgccacgttgtgctgagccaggacatcccgcacatctttgcactgaccctgttt gaggactacgtctactggaccgactgggaaacaaagtccattaaccgagcccacaagacc acgggcaccaacaaaacgctcctcatcagcacgctgcaccggcccatggacctgcatgtc ttccatgccctgcgccagccagacgtgcccaatcacccctgcaaggtcaacaatggtggc tgcagcaacctgtgcctgctgtcccccgggggagggcacaaatgtgcctgccccaccaac ttctacctgggcagcgatgggcgcacctgtgtgtccaactgcacggctagccagtttgta tgcaagaacgacaagtgcatccccttctggtggaagtgtgacaccgaggacgactgcggg gaccactcagacgagcccccggactgccctgagttcaagtgccggcccggacagttccag tgctccacaggtatctgcacaaaccctgccttcatctgcgatggcgacaatgactgccag gacaacagtgacgaggccaactgtgacatccacgtctgcttgcccagtcagttcaaatgc accaacaccaaccgctgtattcccggcatcttccgctgcaatgggcaggacaactgcgga gatggggaggatgagagggactgccccgaggtgacctgcgcccccaaccagttccagtgc tccattaccaaacggtgcatcccccgggtctgggtctgcgaccgggacaatgactgtgtg gatggcagtgatgagcccgccaactgcacccagatgacctgtggtgtggacgagttccgc tgcaaggattcgggccgctgcatcccagcgcgttggaagtgtgacggagaggatgactgt ggggatggctcggatgagcccaaggaagagtgtgatgaacgcacctgtgagccataccag ttccgctgcaagaacaaccgctgcgtgcccggccgctggcagtgcgactacgacaacgat tgcggtgacaactccgatgaagagagctgcacccctcggccctgctccgagagtgagttc tcctgtgccaacggccgctgcatcgcggggcgctggaaatgcgatggagaccacgactgc gcggacggctcggacgagaaagactgcaccccccgctgtgacatggaccagttccagtgc aagagcggccactgcatccccctgcgctggcgctgtgacgcagacgccgactgcatggac ggcagcgacgaggaggcctgcggcactggcgtgcggacctgccccctggacgagttccag tgcaacaacaccttgtgcaagccgctggcctggaagtgcgatggcgaggatgactgtggg gacaactcagatgagaaccccgaggagtgtgcccggttcgtgtgccctcccaaccggccc ttccgttgcaagaatgaccgcgtctgtctgtggatcgggcgccaatgcgatggcacggac aactgtggggatgggactgatgaagaggactgtgagccccccacagcccacaccacccac tgcaaagacaagaaggagtttctgtgccggaaccagcgctgcctctcctcctccctgcgc tgcaacatgttcgatgactgcggggacggctctgacgaggaggactgcagcatcgacccc aagctgaccagctgcgccaccaatgccagcatctgtggggacgaggcacgctgcgtgcgc accgagaaagcggcctactgtgcctgccgctcgggcttccacaccgtgcccggccagccc ggatgccaagacatcaacgagtgcctgcgcttcggcacctgctcccagctctgcaacaac accaagggcggccacctctgcagctgcgctcggaacttcatgaagacgcacaacacctgc aaggccgaaggctctgagtaccaggtcctgtacatcgctgatgacaatgagatccgcagc ctgttccccggccacccccattcggcttacgagcaggcattccagggtgacgagagtgtc cgcattgatgctatggatgtccatgtcaaggctggccgtgtctattggaccaactggcac acgggcaccatctcctaccgcagcctgccacctgctgcgcctcctaccacttccaaccgc caccggcgacagattgaccggggtgtcacccacctcaacatttcagggctgaagatgccc agaggcatcgccatcgactgggtggccggaaacgtgtactggaccgactcgggccgagat gtgattgaggtggcgcagatgaagggcgagaaccgcaagacgctcatctcgggcatgatt gacgagccccacgccattgtggtggacccactgagggggaccatgtactggtcagactgg ggcaaccaccccaagattgagacggcagcgatggatgggacgcttcgggagacactggtg caggacaacattcagtggcccacaggcctggccgtggattatcacaatgagcggctgtac tgggcagacgccaagctttcagtcatcggcagcatccggctcaatggcacggaccccatt gtggctgctgacagcaaacgaggcctaagtcaccccttcagcatcgacgtctttgaggat tacatctatggtgtcacctacatcaataatcgtgtcttcaagatccataagtttggccac agccccttggtcaacctgacagggggcctgagccacgcctctgacgtggtcctttaccat cagcacaagcagcccgaagtgaccaacccatgtgaccgcaagaaatgcgagtggctctgc ctgctgagccccagtgggcctgtctgcacctgtcccaatgggaagcggctggacaacggc acatgcgtgcctgtgccctctccaacgccccccccagatgctccccggcctggaacctgt aacctgcagtgcttcaacggtggcagctgtttcctcaatgcacggaggcagcccaagtgc cgctgccaaccccgctacacgggtgacaagtgtgaactggaccagtgctgggagcactgt cgcaatgggggcacctgtgctgcctccccctctggcatgcccacgtgccggtgccccacg ggcttcacgggccccaaatgcacccagcaggtgtgtgcgggctactgtgccaacaacagc acctgcactgtcaaccagggcaaccagccccagtgccgatgcctacccggcttcctgggc gaccgctgccagtaccggcagtgctctggctactgtgagaactttggcacatgccagatg gctgctgatggctcccgacaatgccgctgcactgcctactttgagggatcgaggtgtgag gtgaacaagtgcagccgctgtctcgaaggggcctgtgtggtcaacaagcagagtggggat gtcacctgcaactgcacggatggccgggtggcccccagctgtctgacctgcgtcggccac tgcagcaatggcggctcctgtaccatgaacagcaaaatgatgcctgagtgccagtgccca ccccacatgacagggccccggtgtgaggagcacgtcttcagccagcagcagccaggacat atagcctccatcctaatccctctgctgttgctgctgctgctggttctggtggccggagtg gtattctggtataagcggcgagtccaaggggctaagggcttccagcaccaacggatgacc aacggggccatgaacgtggagattggaaaccccacctacaagatgtacgaaggcggagag cctgatgatgtgggaggcctactggacgctgactttgccctggaccctgacaagcccacc aacttcaccaaccccgtgtatgccacactctacatggggggccatggcagtcgccactcc ctggccagcacggacgagaagcgagaactcctgggccggggccctgaggacgagataggg gaccccttggcatag |
Protein Sequence |
>4035 : length: 4544 MLTPPLLLLLPLLSALVAAAIDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEA PEICPQSKAQRCQPNEHNCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGC QHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFICGCVEGYL LQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANE TVCWVHVGDSAAQTQLKCARMPGLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDI DDRIFVCNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTK LVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFE NYLYATNSDNANAQQKTSVIRVNRFNSTEYQVVTRVDKGGALHIYHQRRQPRVRSHACEN DQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDGKSCKKPEHELFLVYGKGRPGIIRG MDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDG IHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEKAAQTRKTLIEGKMTHPRAIVVDPLNG WMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVDAFY DRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGSVYRLERGVGGAPPTVT LLRSERPPIFEIRMYDAQQQQVGTNKCRVNNGGCSSLCLATPGSRQCACAEDQVLDADGV TCLANPSYVPPPQCQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRF KCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDD CGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCDNDNDCGDNSDEAGCSHSCSSTQF KCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPLRW RCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENC ESLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDEGELCDQCSLNNGGCSHNCSVAP GEGIVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGWVLEPDGES CRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGLRNTIALDFHLSQSALYWTDVVEDK IYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTT LLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTVHRETGSGGWPNGLT VDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNT LAKANKWTGHNVTVVQRTNTQPFDLQVYHPSRQPMAPNPCEANGGQGPCSHLCLINYNRT VSCACPHLMKLHKDNTTCYEFKKFLLYARQMEIRGVDLDAPYYNYIISFTVPDIDNVTVL DYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSADLPNAHGLAVDWVSRNLFWTSYDTN KKQINVARLDGSFKNAVVQGLEQPHGLVVHPLRGKLYWTDGDNISMANMDGSNRTLLFSG QKGPVGLAIDFPESKLYWISSGNHTINRCNLDGSGLEVIDAMRSQLGKATALAIMGDKLW WADQVSEKMGTCSKADGSGSVVLRNSTTLVMHMKVYDESIQLDHKGTNPCSVNNGDCSQL CLPTSETTRSCMCTAGYSLRSGQQACEGVGSFLLYSVHEGIRGIPLDPNDKSDALVPVSG TSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIY WTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGQYPRIERSRLDG TERVVLVNVSISWPNGISVDYQDGKLYWCDARTDKIERIDLETGENREVVLSSNNMDMFS VSVFEDFIYWSDRTHANGSIKRGSKDNATDSVPLRTGIGVQLKDIKVFNRDRQKGTNVCA VANGGCQQLCLYRGRGQRACACAHGMLAEDGASCREYAGYLLYSERTILKSIHLSDERNL NAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFFSDIHFGNIQQINDDGSRRITIVE NVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDDHPRAFVLD ECQNLMFWTNWNEQHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHRAEKLYFSDATLDK IERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDWVRRAVQRANKHVGSNMKLLRVDI PQQPMGIIAVANDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQDDLTCRAV NSSCRAQDEFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVS NMLWCNGADDCGDGSDEIPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCS ATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNY FACPSGRCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCG DGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTCDD REFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGRCLSSRQWECDG ENDCHDQSDEAPKNPHCTSQEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGCH INECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADVDECSTTFPCSQRCINTH GSYKCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAV ALDFDYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCD KGRDTIEVSKLNGAYRTVLVSSGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSSR SVIVDTKITWPNGLTLDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLF EDYVYWTDWETKSINRAHKTTGTNKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGG CSNLCLLSPGGGHKCACPTNFYLGSDGRTCVSNCTASQFVCKNDKCIPFWWKCDTEDDCG DHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKC TNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCV DGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQ FRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRWKCDGDHDC ADGSDEKDCTPRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQ CNNTLCKPLAWKCDGEDDCGDNSDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTD NCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDP KLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINECLRFGTCSQLCNN TKGGHLCSCARNFMKTHNTCKAEGSEYQVLYIADDNEIRSLFPGHPHSAYEQAFQGDESV RIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISGLKMP RGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDW GNHPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPI VAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKFGHSPLVNLTGGLSHASDVVLYH QHKQPEVTNPCDRKKCEWLCLLSPSGPVCTCPNGKRLDNGTCVPVPSPTPPPDAPRPGTC NLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPT GFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENFGTCQM AADGSRQCRCTAYFEGSRCEVNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSCLTCVGH CSNGGSCTMNSKMMPECQCPPHMTGPRCEEHVFSQQQPGHIASILIPLLLLLLLVLVAGV VFWYKRRVQGAKGFQHQRMTNGAMNVEIGNPTYKMYEGGEPDDVGGLLDADFALDPDKPT NFTNPVYATLYMGGHGSRHSLASTDEKRELLGRGPEDEIGDPLA |