| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 4775 |
Name | NFATC3 |
Synonym | NFAT4|NFATX;nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3;NFATC3;nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
Definition | NF-ATc3|T cell transcription factor NFAT4|nuclear factor of activated T-cells c3 isoform IE-Xa|nuclear factor of activated T-cells, cytoplasmic 3 |
Position | 16q22.2 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | NFATc3 mediates chronic hypoxia-induced pulmonary arterial remodeling with alpha-actin up-regulation. |
PH | NFATc3 is required for chronic hypoxia-induced pulmonary hypertension in adult and neonatal mice. |
PH | Supplemental Table 1: A list of genes and functional categories that comprises a PHrelevant gene module (PH-module). |
| More detail of all Human literatures about NFATC3 | |
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Pathways and Diseases |
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Pathway | VEGF signaling pathway;KEGG PATHWAY;hsa04370 |
Pathway | Axon guidance mediated by netrin;PANTHER;P00009 |
Pathway | B cell receptor signaling pathway;KEGG PATHWAY;hsa04662 |
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | T cell receptor signaling pathway;KEGG PATHWAY;hsa04660 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | T cell activation;PANTHER;P00053 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Role of Calcineurin-dependent NFAT signaling in lymphocytes;PID Curated;200076 |
Pathway | FOXM1 transcription factor network;PID Curated;200120 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | Natural killer cell mediated cytotoxicity;KEGG PATHWAY;hsa04650 |
Pathway | B cell activation;PANTHER;P00010 |
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External Links |
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Links to Entrez Gene | 4775 |
Links to all GeneRIF Items | 4775 |
Links to iHOP | 4775 |
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Sequence Information |
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Nucleotide Sequence |
>4775 : length: 3207 atgactactgcaaactgtggcgcccacgacgagctcgacttcaaactcgtctttggcgag gacggggcgccggcgccgccgcccccgggctcgcggcctgcagatcttgagccagatgat tgtgcatccatttacatctttaatgtagatccacctccatctactttaaccacaccactt tgcttaccacatcatggattaccgtctcactcttctgttttgtcaccatcgtttcagctc caaagtcacaaaaactatgaaggaacttgtgagattcctgaatctaaatatagcccatta ggtggtcccaaaccctttgagtgcccaagtattcaaattacatctatctctcctaactgt catcaagaattagatgcacatgaagatgacctacagataaatgacccagaacgggaattt ttggaaaggccttctagagatcatctctatcttcctcttgagccatcctaccgggagtct tctcttagtcctagtcctgccagcagcatctcttctaggagttggttctctgatgcatct tcttgtgaatcgctttcacatatttatgatgatgtggactcagagttgaatgaagctgca gcccgatttacccttggatcccctctgacttctcctggtggctctccagggggctgccct ggagaagaaacttggcatcaacagtatggacttggacactcattatcacccaggcaatct ccttgccactctcctagatccagtgtcactgatgagaattggctgagccccaggccagcc tcaggaccctcatcaaggcccacatccccctgtgggaaacggaggcactccagtgctgaa gtttgttatgctgggtccctttcaccccatcactcacctgttccttcacctggtcactcc cccaggggaagtgtgacagaagatacgtggctcaatgcttctgtccatggtgggtcaggc cttggccctgcagtttttccatttcagtactgtgtagagactgacatccctctcaaaaca aggaaaacttctgaagatcaagctgccatactaccaggaaaattagagctgtgttcagat gaccaagggagtttatcaccagcccgggagacttcaatagatgatggccttggatctcag tatcctttaaagaaagattcatgtggtgatcagtttctttcagttccttcaccctttacc tggagcaaaccaaagcctggccacacccctatatttcgcacatcttcattacctccacta gactggcctttaccagctcattttggacaatgtgaactgaaaatagaagtgcaacctaaa actcatcatcgagcccattatgaaactgaaggtagccgaggggcagtaaaagcatctact gggggacatcctgttgtgaagctcctgggctataacgaaaagccaataaatctacaaatg tttattgggacagcagatgatcgatatttacgacctcatgcattttaccaggtgcatcga atcactgggaagacagtcgctactgcaagccaagagataataattgccagtacaaaagtt ctggaaattccacttcttcctgaaaataatatgtcagccagtattgattgtgcaggtatt ttgaaactccgcaattcagatatagaacttcgaaaaggagaaactgatattggcagaaag aatactagagtacgacttgtgtttcgtgtacacatcccacagcccagtggaaaagtcctt tctctgcagatagcctctatacccgttgagtgctcccagcggtctgctcaagaacttcct catattgagaagtacagtatcaacagttgttctgtaaatggaggtcatgaaatggttgtg actggatctaattttcttccagaatccaaaatcatttttcttgaaaaaggacaagatgga cgacctcagtgggaggtagaagggaagataatcagggaaaaatgtcaaggggctcacatt gtccttgaagttcctccatatcataacccagcagttacagctgcagtgcaggtgcacttt tatctttgcaatggcaagaggaaaaaaagccagtctcaacgttttacttatacaccagtt ttgatgaagcaagaacacagagaagagattgatttgtcttcagttccatctttgcctgtg cctcatcctgctcagacccagaggccttcctctgattcagggtgttcacatgacagtgta ctgtcaggacagagaagtttgatttgctccatcccacaaacatatgcatccatggtgacc tcatcccatctgccacagttgcagtgtagagatgagagtgttagtaaagaacagcatatg attccttctccaattgtacaccagccttttcaagtcacaccaacacctcctgtggggtct tcctatcagcctatgcaaactaatgttgtgtacaatggaccaacttgtcttcctattaat gctgcctctagtcaagaatttgattcagttttgtttcagcaggatgcaactctttctggt ttagtgaatcttggctgtcaaccactgtcatccataccatttcattcttcaaattcaggc tcaacaggacatctcttagcccatacacctcattctgtgcataccctgcctcatctgcaa tcaatgggatatcattgttcaaatacaggacaaagatctctttcttctccagtggctgac cagattacaggtcagccttcgtctcagttacaacctattacatatggtccttcacattca gggtctgctacaacagcttccccagcagcttctcatcccttggctagttcaccgctttct gggccaccatctcctcagcttcagcctatgccttaccaatctcctagctcaggaactgcc tcatcaccgtctccagccaccagaatgcattctggacagcactcaactcaagcacaaagt acgggccaggggggtctttctgcaccttcatccttaatatgtcacagtttgtgtgatcca gcgtcatttccacctgatggggcaactgtgagcattaaacctgaaccagaagatcgagag cctaactttgcaaccattggtctgcaggacatcactttagatgatgaccaatttatatct gacttggaacaccagccatcaggttcagcagagaaatggcctaaccacagtgtgctctca tgtccagctcctttctggagaatctag |
Protein Sequence |
>4775 : length: 1068 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE PNFATIGLQDITLDDDQFISDLEHQPSGSAEKWPNHSVLSCPAPFWRI |